centrosome

1. Aurora a is involved in centrosome separation, maturation, and spindle assembly and stability.: Auroraa涉及到中心体分离，成熟和纺锤体聚集以及稳定。

2. Aurora a is involved in centrosome separation, maturation, and spindle assembly and stability.: 极光激酶A参与中心体分离、成熟和纺锤体组装及稳定。

3. IntroductionThe centrosome is the major microtubule organizing center (MTOC) of mammalian cells.: 中心体是哺乳类细胞主要的微管组织中心。

4. Malfunctions in centrosome cohesion and separation, in fact, have been seen in many solid tumors.: 事实上，在很多实体瘤中都发现过中心体连接和分离的机能失常。

5. They form a connection between the starting point in the chromosomes, the kinetochore, and the centrosome.: 他们将染色体、着丝粒和中心体的起点连接起来。

6. Overexpression of STK15 induces increased Numbers of centrosome, aneuploidy, and transformation of the cells.: STK15过表达诱导中心体数目增多，异倍体形成和细胞转化。

7. The coordination of the centrosome cycle and cell cycle ensures an accurate distribution of genetic material.: 中心体周期和细胞周期相互配合以保证遗传物质的精确分配。

8. Many centrosome-related proteins and kinases have been found to regulate different steps of centrosome duplication.: 现已发现了许多中心体蛋白及与中心体复制相关的蛋白激酶，调控着中心体复制的各个步骤。

9. With development of the research, the complicated function of centrosome and its im-portance have gradually been realized.: 随着研究的进展，人们不断认识到中心体的复杂功能及其重要性。

10. The study of regulation mechanism about centrosome replication can play an important role in early diagnosis and treatment of tumor.: 研究中心体复制调控机制，对肿瘤的早期诊断和治疗有重要的作用。

11. So gene instability of tumor cells may be closely correlated with centrosome abnormality, which is a common feature of malignant tumor cells.: 因此肿瘤细胞基因不稳定可能与中心体异常密切相关。中心体异常是恶性肿瘤细胞的普遍特征。

12. Prior to cell pision it replicates, and the sister centrioles move to opposite ends of the cell to lie within the spindle - organizing structure, the centrosome.: 它在细胞分裂之前复制，其中一个中心粒移向细胞的另一端，组织纺锤体和中心体。

13. The centrosome, the major microtubule organizing center regulates cell pision through forming bipolar mitotic spindles and plays an essential role in the maintenance of chromosomal stability.: 中心体作为细胞的主要微管组织中心，在细胞周期过程中建立两极纺锤体，调节细胞有丝分裂，从而对维持染色体的稳定起着重要的作用。

14. More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis, it refers to multiple genes abnormity, mainly separated into oncogene and tumor suppressor gene.: 中心体异常与肿瘤发生的相关性已越来越受到人们的重视。

15. More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis, it refers to multiple genes abnormity, mainly separated into oncogene and tumor suppressor gene.: 中心体异常与肿瘤发生的相关性已越来越受到人们的重视。

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