Objective To explore the immunotherapeutic strategy based on SSX tumor gene family by the CTL epitope prediction of the members of SSX tumor gene family and affinity assay of the epitope combining with MHCⅠ molecule.
目的通过对肿瘤基因SSX家族不同成员进行CTL表位预测,并对其与MHC-Ⅰ亲和力进行分析,为探索基于SSX肿瘤基因家族的免疫治疗奠定基础。
Several computer algorithms are currently being used for epitope prediction of various major histocompatibility complex (MHC) class I and II molecules, based either on the analysis of natural MHC liga.
计算机算法与实验技术相结合的方法,已广泛用于各种免疫相关抗原T细胞表位的鉴定,对现在可获得的计算机预测方法,以及计算机算法与实验相结合鉴定T细胞表位的方法进行了综述,主要内容包括表位预测及抗原加工处理的预测。
Methods Codon TGC (cysteine) was mutated to GGC ( glycine) through site-directed mutagenesis PCR and the selection of the mutated site was based on computer-assisted epitope prediction.
方法在对蛋白质序列进行计算机表位预测及生物学特性分析的基础上,利用PCR的定点诱变技术,使原始基因序列中编码半胱氨酸的TGC突变为编码甘氨酸的GGC,克隆并表达了该基因编码的蛋白质。
In order to predict more accurately whether the primary version of the fault-tolerant scheduling algorithm in software fault-tolerant model is executable,a new algorithm named prediction-table based algorithm(PTBA) is put forward,in which the executing situation of tasks between the current time and the notification time of alternate version is fully considered.
为了更精确地预测软件容错模型中的容错实时调度算法主部分可否执行,提出了基于预测表的容错调度算法(PTBA)。
Two algorithms schedule tasks with the help of prediction-table,which is created for the released primary and contai.
算法考虑当前时间至替代部分通知时间之间的任务执行情况,通过构建预测表对待执行主部分的可执行性进行精确预测。
Screening of mimic epitope for MUC1 based on prediction of the antigenic epitope
基于抗原表位预测的MUC1模拟肽表位筛选
Application of PLS Method in the T Cell Epitopes Prediction
PLS方法在T细胞表位预测中的应用
Progress of T cell epitope prediction
T细胞抗原表位预测的研究方法进展
Prediction of Urease Subunit B Epitopes of Helicobacter Pylori and Epitope Screening by Phage Display;
幽门螺杆菌UreB抗原表位预测及其有效表位噬菌体展示的筛选
Prediction and Comparison of Related B Cell Epitopes for Hepatitis B Virus e Antigen and c Antigen
乙型肝炎病毒e、c抗原的B细胞表位预测及其表位比较研究
Detection Autoantibodies to Human MCHR1 in Sera of Patients with Vitiligo and Prediction, Expression of B Cell Epitopes of Human MCHR1;
人MCHR1自身抗体在白癜风患者中检测及其B细胞表位预测与表达
Study on Establishing Novel CTL Epitopes Mapping Algorithm by Soft Docking Simulation;
基于柔性分子对接的CTL表位预测方法研究
The SVM Method Applying in the T Cell Epitopes Prediction
支持向量机方法在T细胞表位预测中的应用
Hepatitis C Virus Genotyping and Epitope Prediction Based on Genotype
HCV基因分型及基于基因型的抗原表位预测研究
Prediction and Screening of HA Epitopes in H5N1 Subtype Virus
H5N1亚型禽流感病HA蛋白抗原表位预测与筛选
Prediction of B cell epitopes for hemagglutinin of the influenza A(H1N1) virus
甲型H1N1流感病毒血凝素的B细胞抗原表位预测
Prediction and Analysis of B Cell Epitopes for the M Protein of TGEV
猪流行性腹泻病毒M蛋白B细胞表位预测分析
Prediction of the common B cell epitopes derived from the tumor antigen MAGE-A sub-family
肿瘤抗原MAGE-A亚家族共同B细胞表位预测及分析
Prediction of the Secondary Structure and B-cell Antigen Epitope on Trichosanthin
天花粉蛋白的二级结构和B细胞抗原表位预测
Prediction of B Cell Epitope for Hepatitis B Virus e Antigen
乙型肝炎病毒e抗原的B细胞表位预测
Prediction of the B Cell Epitope for the FedF of Esherichia coli Eliciting Edema of Piglet
猪水肿病大肠杆菌FedF的B细胞抗原表位预测
Prediction of CTL Epitopes Based on Modified Artificial Neural Network;
基于改进的神经网络方法预测CTL表位
Prediction and Identification of B-Cell Epitopes Derived from HPV18E7
HPV18型E7抗原B细胞表位的预测与鉴定