Recombinant Human Activated Protein C(rhAPC),a drug treating for severe sepsis,had been suggested that its marketing strategy may has affected the professional organization on developing and implementing related guidelines.
重组人类活性蛋白C(rhAPC)为治疗重症脓毒症的药物,目前有证据表明rhAPC的市场策略有可能已经影响到专业机构诊治指南的制定与执行;rhAPC的临床疗效亦未能被大型临床试验继续证实,因此目前rhAPC的临床应用以及疗效评价要慎重进行。
The current incidence of sepsis is at least 240 patients per 100,000 people in the United States population,whereas for severe sepsis it is between 51 and 95 patients per 100,000 people.
研究背景脓毒症(sepsis)是病原微生物入侵机体后引起的全身炎症反应综合征(SIRS),其后续症包括重症脓毒症(severe sepsis)、脓毒症休克(septic shock)、多器官功能不全(MODS)。
Effects of some uremic toxins on erythropoietin receptor of CFU-E of rats in vitro;
尿毒症毒素对大鼠培养骨髓细胞红细胞生成素受体的影响
Significance and Changes of Serum Lipopolysaccharide Binding Protein and Soluble CD14 in Patients with Severe Sepsis;
重症脓毒症患者LBP和sCD14变化及意义
Dynamic Changes and Clinical Meanings of Immunological in Severe Sepsis Postoperative Patients;
腹部重症脓毒症患者术后机体免疫功能的变化
The Effects of High Volume Hemofiltration on IL-18 in Plasma of Patients with Severe Sepsis;
高容量血液滤过（HVHF）对重症脓毒症患者血浆细胞因子IL-18的影响
Effect of intensive insulin therapy at the early stage on the prognosis and serum IL-6 levels in patients with severe sepsis
早期强化胰岛素治疗对重症脓毒症患者血清IL-6及预后的影响
Guidelines of Severe Sepsis and Septic Shock:2008(Pediatric Considerations in Severe Sepsis)
严重脓毒症和脓毒性休克治疗指南2008(儿科部分)
Thrombopoietin Levels Change in Septic Rats and Its Relation to Sepsis Severity;
脓毒症大鼠血小板生成素水平与脓毒症严重程度的关系
The infection of gravest import is burn wound sepsis.
最严重的感染是烧伤创面脓毒症。
Blood Purification in the Treatment of Severe Sepsis;
血液净化在严重脓毒症治疗中的应用
Vascular Endothelial Growth Factor Levels in Severe Sepsis and Its Pathogens Study;
严重脓毒症患者VEGF水平及病原学研究
Severe Sepsis:the implications from diagnostic criteria;
严重脓毒症——评价指标带给我们的启示
The Study of Fluid Resuscitation Therapy on the Treatment of Severe Sepsis and Sepic Shock Patients;
液体复苏对严重脓毒症、脓毒性休克病人的治疗作用的研究
The Efficacy of ITBV and EVLW in Fluid Management on Severe Sepsis/septic Shock
ITBV和EVLW在严重脓毒症/脓毒性休克液体管理中的意义
sepsis agranulocytica
粒细胞缺乏性脓毒症
Clinical significance of detection of thrombus precursor protein in severe sepsis
血栓前体蛋白测定在严重脓毒症中的临床意义
Clinical Effect and Mechanism of Fusu Yin on Treating Severe Sepsis;
复苏饮防治严重脓毒症的疗效及作用机制研究
The Clinical Study of Intensive Insulin Therapy on Severe Sepsis;
强化胰岛素治疗严重脓毒症的临床研究
Clinical Trial of Immunoregulation Therapy in the Patients with Trauma, Severe Sepsis or MODS;
创伤、严重脓毒症和MODS免疫调理治疗的临床研究
Clinical Study on Relationship between Protein C Level and Prognosis in Patients with Severe Sepsis;
严重脓毒症蛋白C水平与预后关系的临床研究