Here we report that growth cones of rat cerebellar axons in culture turned away from a gradient of SDF-1, a chemokine that attracts migrating leukocytes and cerebellar granule cells via a G protein-coupled receptor (GPCR).
以前的证据表明,SDF-1,一种经典的chemokine,能够吸引白细胞和迁移中的神经元,这种作用是通过G蛋白耦联受体介导的。
Regulation of G protein-coupled receptor kinase 5 mRNA and protein level in rat brain by addictive drugs;
成瘾性药物对大鼠脑内G蛋白耦联受体激酶5 mRNA和蛋白水平的调控
Objective To study the function and mechanism of GIT1(G protein coupled receptor kinase interacting protein 1)in osteoblast migration.
目的探索G蛋白耦联受体激酶结合蛋白1(GITI)在成骨细胞迁移中的作用,并分析其机理。
G protein-coupled receptors (GPCRs) which constitute the largest superfamily of receptors in human genome, regulate a variety of physiological functions and pathological processes.
G蛋白偶联受体是体内最大的受体超家族,它们参与调节生物体内多种生理功能与病理过程。
Extra-cellular signals are directly or indirectly transmitted into cells by G protein-coupled receptors(GPCRs).
很多胞外信号直接或间接通过G蛋白偶联受体向胞内传输。
G-protein coupled receptors(GPCRs)belong to the biggest subfamily of transmembran receptors.
G蛋白偶联受体(GPCR s)是最大的细胞膜受体家族,具有七螺旋跨膜肽段结构。
Process of research about G protein-coupled receptor;
G蛋白偶联受体研究进展
A Rapid, Nongenomic Mechanism of Androgens in Prostate Cancer Cells Via a G Protein-Coupled Receptor;
G蛋白偶联受体介导雄激素对前列腺癌细胞快速作用的非基因组机制
G Protein-coupled receptors are a group of drug targets with important physiological functions and of pathological significance.
G蛋白偶联受体具有重要的生理功能和病理意义,已成为一类重要的药物靶点。
Metabotropic glutamate receptors 1/5 (mGluR 1/5) is an important member of family of C G protein coupled receptor (GPCRs).
代谢型谷氨酸受体1/5(mGluR1/5)是G蛋白偶联受体家族C的重要成员之一,该受体及其介导的下游信号在调节神经系统的正常生理功能起着非常重要作用,并与相关神经系统退行性疾病密切相关。
G protein coupled receptors are seven-transmembrance integrated membrane proteins,which mediate numerous cellular signal transduction events triggered by a variety of molecules and compounds such as hormones,neurotransmitters,light,odours and taste.
G蛋白偶联受体(GPCR)是具有7次跨膜螺旋的细胞整合膜蛋白,它们广泛地参与感光、气味、神经传递以及细胞增殖、分化、迁移等各类生理活动的调控,是现代药物研发的重要靶点。
Nerve Growth Cone Guidance Mediated by G Protein-coupled Receptors;
G蛋白耦联受体介导的神经生长锥导向
G-Protein-Coupled Receptor 120-GPR120:Molecular Modeling Studies
G-蛋白偶联受体GPR120分子模建研究
G Protein-coupled Receptors Regulate Amyloid-β Production;
G蛋白偶联受体调节β淀粉样蛋白的产生
Effect of G Protein βγ Subunitson Phosphorylation of G-protein Coupled Receptors
G蛋白βγ亚基影响G蛋白偶联受体磷酸化的作用研究
G protein coupled receptorsare important receptor proteins in cell surface.
G蛋白偶联受体是细胞表面一类重要的受体蛋白。
Cloning, Analyzing and Ligand Screening of hGPCRc as a Member of Human Orphan G Protein-coupled Receptor;
孤儿G蛋白偶联受体hGPCRc克隆、分析及配基筛选
Development of Drug Screening Models Targeted to G Protein-Coupled Receptors Based on Scintillation Proximity Assay;
针对G蛋白偶联受体的SPA药物筛选技术研究
Functional Analysis of Two Putative G-protein Coupled Receptors in Magnaporthe Grisea;
稻瘟病菌两个假定G蛋白偶联受体的功能分析
Study of the Specificity of GPCR Regulation of GIRK Channels;
G蛋白偶联受体调节GIRK通道的特异性研究
Isolation Characterization and Expression of cDNA Clones Encoding a G Protein-coupled Receptor Kinase of the Ascidian Ciona Intestinalis;
海鞘G蛋白偶联受体激酶cDNA的克隆定性与表达
Prediction of Functional Sites and SNPs in G Protein-coupled Receptors;
G蛋白偶联受体功能位点与功能性SNPs的预测
The Fine Research of the Activation Mechanism of GPCR Family C
C族G蛋白偶联受体激活机制的精细研究
Modulatory role of lipid rafts on GPCR signaling
脂筏在G蛋白偶联受体信号转导中的调控作用
Expression and ELISA Analysis of the Recombinant Rats G-protein Coupled Receptors Kinase 5
大鼠G-蛋白偶联受体激酶5重组蛋白的表达及ELISA检测
The Repertoire of G-Protein-Coupled Receptors in Xenopus Tropicalis
热带爪蟾G蛋白偶联受体的系统发生及比较基因组学分析
The expressions of G protein-coupled receptor 30 and phosphorylated AKT in endometrial adenocarcinoma
G蛋白偶联受体30和磷酸化AKT在子宫内膜腺癌中表达及意义
Signal Pathway and Physiological Functions of Free Fatty Acids Mediated by G Protein-coupled Receptors
G蛋白偶联受体介导游离脂肪酸的信号通路及生理功能
Effect of G Protein βγ Subunits on Phosphorylation of M2 Receptor
G蛋白β、γ亚基对M2受体的磷酸化的影响