hepatica incubated in Rohrbacher solution added different concentrations of niclofolan and albendazole were determined by reverse_phase HPLC by precolumn fluorescence derivalization with θPA_β_ME.
用HPLC法测定在加了不同浓度硝氯酚和丙硫咪唑的R氏液中体外培养的肝片吸虫体内γ_氨基丁酸(GABA)的含量,结果证实硝氯酚能极显著地降低肝片吸虫体内GABA含量,丙硫咪唑对肝片吸虫体内GABA含量无显著性影响,硝氯酚的抗肝片吸虫作用可能与GABA有关,丙硫咪唑的抗吸虫作用可能与GABA无关。