NPS precursor and NPS receptor (NPSR) mRNA were found in some brain area such as amygdala, the ventral tegmental area (VTA) and the substantia nigra, which was thought to modulate rewarding properties of drugs.
NPS前体和NPS受体(NPSR)mRNA在杏仁核(amygdala)、中脑腹侧被盖区(ventral tegmental area,VTA)和黑质(substantia nigra,SN)中都有分布,而这些区域与药物奖赏效果的调节相关,说明NPS可能会影响体内的奖赏系统。