We report here a simple and effective method to assess the CAG repeat size of HD gene for gene diagnosis of Huntington disease,Genomic DNA sequences in polymorphic CAG repeat HD gene was amplified by PCR with TaKaRa LA Taq DNA polymerase and GC buffer.
为了简单高效检测HD基因开放阅读框5'端(CAG)n三核苷酸重复序列,建立快速准确的亨廷顿病(Hun-tington disease,HD)基因诊断方法,应用TaKaRa LATaqDNA聚合酶配合GC buffer扩增HD基因包含(CAG)n重复序列的目的片段,非变性聚丙烯酰胺凝胶电泳检测后回收(CAG)n拷贝数异常增多的目的片段,再次PCR扩增后将产物连接至T载体,进行DNA测序确定CAG的拷贝数。
Using the molecular biological technology,we established the molecular diagnostic methods for Wilson’s disease, Huntington disease and spinocerebellar ataxias.
亨廷顿病(Huntington disease,HD)是一种呈常染色体显性遗传的中枢神经系统退行性病变,临床表现主要为进行性的运动障碍、精神异常和智能衰退。
Impaired function of pancreatic β cells in the R6/2 transgenic mouse model of Huntington's disease
R6/2型亨廷顿病转基因小鼠胰岛β细胞功能损伤
Effect of Chinese compound 962 capsule on behavior deficit in Huntington’s disease model rats
亨廷顿病大鼠行为学改变及中药962胶囊干预
Study on the Modifiers of Huntington Disease and Neuroprotection of 3-nitropropionic Acid Preconditioning;
亨廷顿病修饰基因的研究及3-硝基丙酸预处理的神经保护作用
Molecular Diagnostic Methods for Wilson Disease, Huntington Disease and Spinocerebellar Ataxia
肝豆状核变性、亨廷顿病和遗传性共济失调的分子诊断方法研究
Impaired function of pancreatic β cells in the R6/2 transgenic mouse model of Huntington's disease
R6/2型亨廷顿病转基因小鼠胰岛β细胞功能损伤
She declined genetic testing for HD, principally out of concern fora relative who might have difficulty with employment or insurance.
她拒绝接受亨廷顿病的遗传学检查，主要是由于担心会带来有就业及保险方面的困难。
Their research suggests a possible means by which Huntington's disease functions.
研究也表明了亨廷顿疾病发病的一个可能途径。
A novel therapeutic disaccharide for Huntington's disease by inhibiting aggregation and delaying pathology
海藻糖治疗亨廷顿蛋白构象病的研究进展
Ellsworth Hun tington,
埃尔?斯沃斯?亨廷顿（1876-1974）
Early onset Huntington disease: A neuronal degeneration syndrome
早期发病的亨廷顿舞蹈病:一种神经元退行性改变综合征
The Study of Huntington s Disease s Rat Model Treated with Different 3-Nitropropionic Acid Doses;
3-硝基丙酸改良剂量建立亨廷顿舞蹈病大鼠模型研究
Study of the Rat Model of Huntington's Disease Induced by 3-Nitropropionic Acid
三硝基丙酸诱导大鼠亨廷顿氏病模型的改进研究
Huntington-Heberlein process
亨廷顿－希伯莱因重介质选矿法
A Study of Samuel Huntington s Theory of Democratic Consolidation;
塞缪尔·亨廷顿的民主巩固理论研究
Think about Samuel ·Huntington s Theory of Clash of Civilization;
反思塞缪尔·亨廷顿的“文明的冲突”
Text Interpretation:An Imagined Global War of 2010 Proposed by S.P. Huntington;
文本解读:亨廷顿虚拟“2010年全球战争”
Truths and Prejudices: the Democracy of Taiwan In Huntington s View;
真知与偏见:亨廷顿眼中的台湾民主
A Comment on Huntington s Thinking on Political Development and Political Stability;
亨廷顿政治发展与政治稳定思想述评
For example, Parkinson's, Alzheimer's and Huntington's diseases are caused by the death of specific cells in the brain.
例如，帕金森氏症、阿尔茨海默氏症和亨廷顿疾病，都是由特殊脑细胞死亡引起的。