1.真挚的;真诚的
2.〈古〉纯粹的,不混杂...的 (of)
1.talking and acting in a way that shows you really mean what you say and do; sincere words, feelings, ways of behaving, etc. are true and honest
1.First of all, please allow me to offer my sincerest regret to you, for the very fact that thee-mail should have been sent half an year ago.
首先我要向您致以最真诚的歉意，本来这封邮件是要在半年前就要发给您的，由于技术以及个人其他的原因，一直拖到了今天。
2.You could walk into the office one day, only to be sent away with a pink slip and your employer's "sincerest regrets. "
那你某天走进办公室之后，就可以带着解雇通知书和他的“万分惋惜”离开了。
3.but I must be a blockhead indeed, if, whatever befell me, I could think of your kindness and sympathy without the sincerest gratitude.
不管出现什么情况，我一想到你对我的好意和盛情，而能不感到由衷的感激，那我一定是个十足的傻瓜。
4.Dear teachers, the schoolmates, everybody good morning! Is willing us the performance to be able to deliver we sincerest blessing today!
亲爱的老师，同学们，大家早上好！愿我们今天的表演能送上我们最诚挚的祝福！
5.Needless to say, there is no excuse for this and I extend my sincerest apologies along with the attached check.
不必多说，关于这件事我是毫无托词而言的。在此，表达我最诚挚的道歉并随函附了一张支票。
6.Please accept my sincerest apologies since, due to a previous engagement, I will not be able to join you.
请接受我最真诚的道歉。由于我已与他人事先有约，所以不能参加你们的活动。
7.Imitation is the sincerest form of flattery indeed, but remember that Facebook's user base is still much larger than Twitter's.
的确，模仿就是最诚恳的赞美，但别忘了，Facebook的用户要比Twitter用户多。
8.My sincerest hope is to speak to you of the vast and unfailing presence of Love, accessible to you at any time.
我最真诚的希望就是告诉你们：那无穷的、永恒的爱，任何时候都是对你们开放的。
9.Once again, I beg you accept sincerest apologies for the unfortunate carelessness, and I await anxiously your next move.
因为我不幸粗心大意，再次恳求你接受我最真诚的道歉，我急切地等待你的下一步。
10.It's the endless time that is always flowing away, But the sincerest affection Between you and me will remain and last long.
流走的是悠悠岁月，留下来的却是你我那份最真挚的情谊。