1.【生化】水蛭素
1.a substance produced by the salivary glands of leeches that prevents blood from clotting
1.As a direct thrombin inhibitor, recombinant hirudin(r-hirudin) has played an important role in clinical use.
作为直接凝血酶抑制剂，重组水蛭素在临床上的应用已越来越重要。
2.In addition, the bleeding liability induced by the recombinant fusion protein was less than that of hirudin.
等摩尔浓度下，融合蛋白的出血倾向也明显小于水蛙素。
3.OBJECTIVE Progress in different routes of administration and formulations for Hirudin are reviewed.
目的阐述水蛭素不同给药途径及相关剂型的研究进展。
4.The anticoagulation effect of hirudin was better than dipyridamole (P01).
水蛭素抗凝作用明显强于潘生丁（P0.01）。
5.Hirudin was proved to be highly purified by SDS-PAGE analysis.
经SDS-PAGE电泳分析证实得到水蛭素纯度较高。
6.Hirudin has good pharmacological action, which is widely used in clinical practice.
水蛭素具有较好的药理作用，其药源丰富，在临床上应用广泛。
7.OBJECTIVE: To investigate the protective effect of hirudin on random skin flap congestion.
目的：观察水蛭素对大鼠随意皮瓣淤血模型成活保护作用。
8.Methods Stability of hirudin was based on influencing factor experiment, accelerating experiment and long-term experiment.
方法通过影响因素实验，加速实验和长期稳定性实验，对其外观性状、溶解性、干燥失重、活性等进行研究。
9.Objective: To investigate the anti-tumor mechanism of hirudin.
目的：探讨复方水蛭素抗肿瘤的作用机理。
10.ConclusionThe experiments show that hirudin active factors have strong inhibition effect on S180 Tumor and CAM angiogenesis.
结论实验表明，水蛭素活性因子对S180肿瘤和CAM新生血管具有较强的抑制作用。