1.Cetirizine hydrochloride, an antihistamine, is chiral whose (R)-( + )-enantiomer has no biological activity.
盐酸西替利嗪是第二代抗组胺药,具有旋光性,其中右旋西替立嗪无抗组胺作用。
2.Indeed, small amount (less than 5%) of the distomer (inactive enantiomer) could be detected either in UV or mass-spectrometry.
事实上,少量的(低于5%)(无效对映异构体)可以在紫外线或质谱分析检测。
3.RESULTS & CONCLUSION: The enantiomer of asymmetric drugs assume complex pharmacokinetic and pharmacodynamic characteristics.
结果与结论:手性药物对映体表现出错综复杂的药代动力学和药效学特征。
4.A practical chiral capillary electrophoresis method was established for the determination of the(R)-enantiomer in zolmitriptan.
建立了毛细管电泳法检测手性药物佐米曲普坦中其(R)-对映异构体杂质。
5.Enantiomer accounts for quite large percentage in medicines, which has great difference in pharmacodynamics and pharmacokinetics.
对映异构体在药物中占有很大比例,对映异构体药物在体内往往呈现很大药效学、药动学差异。
6.It was found that resolution of enantiomer of neutral compound was enhanced by adding certain amount of methanol.
同时发现,一定含量的甲醇可以提高中性化合物对映体分离度。
7.Chiral, single enantiomer pharmaceuticals have become increasingly more important.
手性,单一对映体药物已成为越来越重要。
8.The separation of enantiomer in chiral drugs is an important subject of research in pharmaceutical field.
手性药物对映体分离是药学领域重要的研究课题。
9.Thorough study of enantiomer of asymmetric drugs will exert great influence on rational use of asymmetric drugs.
手性药物对映体的深入研究,将对临床合理应用手性药物产生深远的影响。
10.Enantiomer fraction (EF) is used to investigate the atmospheric transport and exchange of chiral pesticides with soil and water.
利用手性农药的对映体分数可研究农药在土壤-大气,水体-大气间的迁移过程;