a serious/severe/considerable disadvantage
重大的不利条件
One major disadvantage of the area is the lack of public transport.
这个地区的一大不便之处就是缺少公共交通工具。
There are disadvantages to the plan.
这个计划有诸多不利因素。
What's the main disadvantage ?
主要的不利条件是什么？
I was at a disadvantage compared to the younger members of the team.
与队里较年轻的队员相比，我处于不利地位。
The fact that he didn't speak a foreign language put him at a distinct disadvantage .
他不会说外语使他处于明显的不利地位。
I hope my lack of experience won't be to my disadvantage .
但愿我的经验不足不会使我吃亏。
The advantages of the scheme far outweighed the disadvantages .
这个计划的优点远远超过了缺点。
Many children in the class suffered severe social and economic disadvantage.
班上许多孩子都来自社会地位低下、经济困难的家庭。
1.不利,不便;不利的处境[地位]
2.(名誉,信用等的)损害,损失
1.使不利,使吃亏
1.something that makes someone or something less effective, successful, or attractive
1.to make it more difficult for someone or something to succeed than other people or things
1.The only disadvantage is that it may trigger the selection of new biotypes that are able to attack the resistance cultivars.
唯一不利之处是可能促进新生物型的选择，危害抗虫品种。
2.At the very least being public does not seem to have been a disadvantage for GLG.
至少把公司的情况公之于众看起来并没有对GLG公司有什么不利。
3.But we also have to see that, comparing with the other medium , newspaper are also that existence its certain disadvantage.
但我们也必须要看到，比起其他媒介，报纸也是存在着它的一定的不足的。
4.The greatest disadvantage of a person is not selfish, passionate, brutal, capricious, but a paranoid love do not love themselves.
一个人最大的缺点不是自私、多情、野蛮、任性，而是偏执的爱一个不爱自己的人。
5.A. Until about the 1960s, the conventional wisdom was that bilingualism was a disadvantage. Some of this was xenophobia.
直到大约上世纪60年代以前，人们还普遍认为双语能力是一种劣势，其中有排外情绪作祟。
6.We grow out of having short bandy legs and no teeth. We would also grow out of having a naked skin if it proved to be a disadvantage.
我们出生时都是四肢短小、没有牙齿，如果没有毛发是个缺点的话，那么我们出生时也会如此。
7.But it has a big disadvantage. It doesn't allow you to run both operating systems simultaneously, or copy and paste material between them.
但它也有一个巨大的弱点，不允许同时运行两个系统，也不能在两大系统之间复制粘贴。
8.He couldn't speaking English two years ago, it made him in a disadvantage status when he in the American.
他两年前不会说英语，这使他当时在美国处于不利地位。
9.Any other stratis at a disadvantage to someone who starts out with fast tengu.
任何其他开始处于劣势的人谁启动了快速天狗。
10.These operated to the disadvantage of the South, a largely agricultural area, which had to pay high prices for imports.
这抓住了南方的软肋，因为南方是大片的农地，他们不得不为高价进口货物买单。