1-Propene, 3-chloro-

物化性质

外观与性状：

透明液体

密度：

0.939 g/mL at 25 °C(lit.)

熔点：

-136 °C

沸点：

44-46 °C(lit.)

闪点：

−20 °F

水溶解性：

3.6 G/L (20 ºC)

折射率：

n20/D 1.414(lit.)

蒸汽压：

417mmHg at 25°C

蒸汽密度：

2.6 (vs air)

存储条件/存储方法：

库房通风低温干燥,与氧化剂、酸类和碱类分开存放

稳定性相关：

1.兼有烯烃和卤代烃的反应性，与卤代氢加成一般生成1,2-二卤化物。低温用浓硫酸处理再用水稀释得到1-氯-2-丙醇。碱性水解生成烯丙醇。与氢氧化钾乙醇溶液反应生成烯丙基乙基醚。与氨反应生成烯丙胺、二烯丙胺和三烯丙胺。与各种有机酸的钠盐在适当的pH值下反应，生成烯丙基酯。

2.稳定性^[26] 稳定

3.禁配物^[27] 强氧化剂、酸类、硝酸、发烟硫酸、氯磺酸、乙烯亚胺、乙烯二胺、碱类、如氢氧化钠

4.避免接触的条件^[28] 受热，接触空气

5.聚合危害^[29] 聚合

6.分解产物^[30] 氯化氢

其它信息：

1.性状：无色透明液体，有不愉快的刺激性气味。^[1]

2.熔点（℃）：-134.5^[2]

3.沸点（℃）：44~45^[3]

4.相对密度（水=1）：0.94^[4]

5.相对蒸气密度（空气=1）：2.64^[5]

6.饱和蒸气压（kPa）：45.2（20℃）^[6]

7.燃烧热（kJ/mol）：-1842.5^[7]

8.临界温度（℃）：241^[8]

9.临界压力（MPa）：4.76^[9]

10.辛醇/水分配系数：1.45~1.93^[10]

11.闪点（℃）：-31.7（CC）；-28.9（OC）^[11]

12.引燃温度（℃）：392^[12]

13.爆炸上限（%）：11.2^[13]

14.爆炸下限（%）：2.9^[14]

15.溶解性：不溶于水，可混溶于乙醇、乙醚、氯仿、石油醚等多数有机溶剂。^[15]

16.黏度（mPa·s,20ºC）：0.3374

17.蒸发热（KJ/mol,b.p.）：24.86

18.生成热（KJ/mol,25ºC,气体）：29.3

19.燃烧热（KJ/mol,25ºC,液体）：1845.5

20.比热容（KJ/(kg·K),40ºC,液体,计算值）：1.65

21.电导率（S/m,0ºC）：<3×10^-9

22.体膨胀系数（K^-1,30ºC）：0.001475

23.相对密度（25℃，4℃）：0.9311

24.常温折射率（n²⁵）：1.4116

25.液相标准热熔(J·mol^-1·K^-1)：112.8

26.气相标准熵(J·mol^-1·K^-1) ：310.35

27.气相标准热熔(J·mol^-1·K^-1)：75.06

安全信息

外观与性状：

透明液体

密度：

0.939 g/mL at 25 °C(lit.)

熔点：

-136 °C

沸点：

44-46 °C(lit.)

闪点：

−20 °F

水溶解性：

3.6 G/L (20 ºC)

折射率：

n20/D 1.414(lit.)

蒸汽压：

417mmHg at 25°C

蒸汽密度：

2.6 (vs air)

存储条件/存储方法：

库房通风低温干燥,与氧化剂、酸类和碱类分开存放

稳定性相关：

1.兼有烯烃和卤代烃的反应性，与卤代氢加成一般生成1,2-二卤化物。低温用浓硫酸处理再用水稀释得到1-氯-2-丙醇。碱性水解生成烯丙醇。与氢氧化钾乙醇溶液反应生成烯丙基乙基醚。与氨反应生成烯丙胺、二烯丙胺和三烯丙胺。与各种有机酸的钠盐在适当的pH值下反应，生成烯丙基酯。

2.稳定性^[26] 稳定

3.禁配物^[27] 强氧化剂、酸类、硝酸、发烟硫酸、氯磺酸、乙烯亚胺、乙烯二胺、碱类、如氢氧化钠

4.避免接触的条件^[28] 受热，接触空气

5.聚合危害^[29] 聚合

6.分解产物^[30] 氯化氢

其它信息：

1.性状：无色透明液体，有不愉快的刺激性气味。^[1]

2.熔点（℃）：-134.5^[2]

3.沸点（℃）：44~45^[3]

4.相对密度（水=1）：0.94^[4]

5.相对蒸气密度（空气=1）：2.64^[5]

6.饱和蒸气压（kPa）：45.2（20℃）^[6]

7.燃烧热（kJ/mol）：-1842.5^[7]

8.临界温度（℃）：241^[8]

9.临界压力（MPa）：4.76^[9]

10.辛醇/水分配系数：1.45~1.93^[10]

11.闪点（℃）：-31.7（CC）；-28.9（OC）^[11]

12.引燃温度（℃）：392^[12]

13.爆炸上限（%）：11.2^[13]

14.爆炸下限（%）：2.9^[14]

15.溶解性：不溶于水，可混溶于乙醇、乙醚、氯仿、石油醚等多数有机溶剂。^[15]

16.黏度（mPa·s,20ºC）：0.3374

17.蒸发热（KJ/mol,b.p.）：24.86

18.生成热（KJ/mol,25ºC,气体）：29.3

19.燃烧热（KJ/mol,25ºC,液体）：1845.5

20.比热容（KJ/(kg·K),40ºC,液体,计算值）：1.65

21.电导率（S/m,0ºC）：<3×10^-9

22.体膨胀系数（K^-1,30ºC）：0.001475

23.相对密度（25℃，4℃）：0.9311

24.常温折射率（n²⁵）：1.4116

25.液相标准热熔(J·mol^-1·K^-1)：112.8

26.气相标准熵(J·mol^-1·K^-1) ：310.35

27.气相标准热熔(J·mol^-1·K^-1)：75.06

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UC7350000

CHEMICAL NAME :

Propene, 3-chloro-

CAS REGISTRY NUMBER :

107-05-1

BEILSTEIN REFERENCE NO. :

0635704

LAST UPDATED :

199801

DATA ITEMS CITED :

75

MOLECULAR FORMULA :

C3-H5-Cl

MOLECULAR WEIGHT :

76.53

WISWESSER LINE NOTATION :

G2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rat

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - guinea pig

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human

DOSE/DURATION :

3000 ppm

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

460 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

11 gm/m3/2H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - ulceration or bleeding from duodenum Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

425 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

11500 mg/m3/2H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

155 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

10500 mg/m3/2H

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

22500 mg/m3/2H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

2066 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

5800 mg/m3/2H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

8 ppm/7H/35D-I

TOXIC EFFECTS :

Liver - other changes Kidney, Ureter, Bladder - other changes Endocrine - changes in spleen weight

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

250 ppm/6H/90D-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9949 mg/kg/13W-I

TOXIC EFFECTS :

Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - sensory change involving peripheral nerve Peripheral Nerve and Sensation - recording from peripheral motor nerve

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1350 mg/kg/9D-I

TOXIC EFFECTS :

Peripheral Nerve and Sensation - structural change in nerve or sheath Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in calcium

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

15300 mg/kg/17W-I

TOXIC EFFECTS :

Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - structural change in nerve or sheath

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

206 mg/m3/6H/13W-I

TOXIC EFFECTS :

Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - muscle weakness

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

8 ppm/7H/35D-I

TOXIC EFFECTS :

Liver - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

206 mg/m3/6H/13W-I

TOXIC EFFECTS :

Spinal Cord - demyelination Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

8 ppm/7H/35D-I

TOXIC EFFECTS :

Liver - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

50 gm/kg/78W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

5880 mg/kg/8W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

78 gm/kg/78W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

DOSE :

300 ppm/7H

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

1200 mg/kg

SEX/DURATION :

female 1-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

4 gm/kg

SEX/DURATION :

female 7-14 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :

Unscheduled DNA synthesis

TEST SYSTEM :

Human HeLa cell

REFERENCE :

CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 20,263,1983 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-STEL 6 mg/m3 (2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 3 mg/m3 (1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 36,39,1985 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 36,39,1985 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 21,251,1977 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 ppm (3 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,8,1971 OSHA PEL (Gen Indu):8H TWA 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3) JAN 1993 OEL-DENMARK:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-FINLAND:TWA 1 ppm (3 mg/m3);STEL 3 ppm (9 mg/m3) JAN 1993 OEL-FRANCE:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-GERMANY:TWA 1 ppm (3 mg/m3);Carcinogen JAN 1993 OEL-HUNGARY:TWA 3 mg/m3;STEL 6 mg/m3 JAN 1993 OEL-INDIA:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-RUSSIA:STEL 0.3 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3) JAN 1993 OEL-TURKEY:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ALLYL CHLORIDE-air:10H TWA 1 ppm;STEL 3 ppmREFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3205 No. of Facilities: 159 (estimated) No. of Industries: 10 No. of Occupations: 15 No. of Employees: 3193 (estimated) No. of Female Employees: 325 (estimated)

毒理学数据：

1、刺激性：家兔经眼：469mg，引起刺激。家兔经皮开放性刺激试验：10mg/24 小时，引起刺激。

2、急性毒性：大鼠经口LD50为700mg/kg；大鼠吸入LD5O：11000mg/m3，2小时；兔经皮LD5O：2066 mg/kg；

3、属低毒类。能强烈地刺激皮肤、眼、鼻和咽喉。麻醉作用弱，对肝脏损害较小，但对肺、肾的损害大。吸入其蒸气会引起头痛、眼花，浓度高时失去知觉。大鼠吸入浓度为945mg/m3的蒸气时，几小时内即可死亡。易被皮肤吸收并迅速分布到整个体内而损害内部组织。工作场所最高容许浓度为3mg/m3（美国）。

4.急性毒性^[16]

LD50：700mg/kg（大鼠经口）；2066mg/kg（兔经皮）

LC50：11000mg/m³（大鼠吸入，2h）

5.刺激性^[17]

家兔经皮：10mg（24h），引起刺激（开放性刺激试验）。

家兔经眼：469mg，引起刺激。

6.亚急性与慢性毒性^[18] 大鼠、小鼠吸入20ppm，每天7h，共90d，未见异常反应；而剂量达50ppm，则引起肝、肾损害。

7.致突变性^[19] 微生物致突变：鼠伤寒沙门菌938μg/皿；大肠杆菌20μl/皿。程序外DNA合成：人HeLa细胞1mmol/L。

8.致畸性^[20] 大鼠孕后6~15d吸入最低中毒剂量（TCLo）300ppm（7h），致肌肉骨骼系统发育畸形。

9.致癌性^[21] IARC致癌性评论：G3，对人及动物致癌性证据不足。

10.其他^[22] 大鼠吸入最低中毒浓度（TCLo）：300ppm（7h）（孕前6~15d），引起肌肉骨骼发育异常。

生态数据：

1.生态毒性^[23]

LC50：21mg/L（96h）（金鱼，静态）；42mg/L（96h）（蓝鳃太阳鱼，静态）；20mg/L（96h）（黑头呆鱼，静态）；250mg/L（24h）（水蚤，静态）

2.生物降解性^[24]

好氧生物降解（h）：168~672

厌氧生物降解（h）：672~2688

3.非生物降解性^[25]

空气中光氧化半衰期（h）：3.03~28.8

一级水解半衰期（h）：335

MSDS

第一部分：化学品名称

海关数据

中国海关编码：2903291000

概述：

2903291000 3-氯-1-丙烯(氯丙烯)。监管条件:无。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途

摘要/Summary：

2903291000 3-chloroprop-1-ene。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0%

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：20.52

2、摩尔体积（cm³/mol）：84.5

3、等张比容（90.2K）：178.9

4、表面张力（dyne/cm）：20.0

5、极化率：8.13

计算化学数据

1.疏水参数计算参考值（XlogP）:1.5

2.氢键供体数量:0

3.氢键受体数量:0

4.可旋转化学键数量:1

5.互变异构体数量:无

6.拓扑分子极性表面积0

7.重原子数量:4

8.表面电荷:0

9.复杂度:17.2

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1