1H-Imidazole,1-[(2-fluorophenyl)(4-fluorophenyl)phenylmethyl]-
- 中文别名：氟曲马唑
- 中文释义：氟曲马唑;氟曲吗唑;1-[(2-氟苯基)(4-氟苯基)(苯基)甲基]咪唑;1-[(2-氟苯基)-(4-氟苯基)苯基甲基]-1H-咪唑
- 英文别名：flutrimazole;
Flutrimazolum [INN-Latin];
Flutrimazol [INN-Spanish];
Flutrimazolum;
1-[(2-fluorophenyl)-(4-fluorophenyl)-phenylmethyl]imidazole;
UR-4056;
1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1H-imidazole;
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole;
Flutrimazole (INN);
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-Imidazol;
Flutrimazol
- CAS No.：119006-77-8
- 分子式：
C22H16F2N2
- 分子量：346.37
- 精确分子量：346.12800
- PSA：17.82000
- InChI：InChI=1/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H
- 分子结构式：
物化性质
- 密度：
- 1.15 g/cm3
- 熔点：
- 161-166ºC
- 沸点：
- 457.1ºC at 760 mmHg
- 闪点：
- 230.3ºC
- 折射率：
- 1.59
- 蒸汽压：
- 4.16E-08mmHg at 25°C
安全信息
- 密度：
- 1.15 g/cm3
- 熔点：
- 161-166ºC
- 沸点：
- 457.1ºC at 760 mmHg
- 闪点：
- 230.3ºC
- 折射率：
- 1.59
- 蒸汽压：
- 4.16E-08mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NI6259450
- CHEMICAL NAME :
- 1H-Imidazole, 1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-
- CAS REGISTRY NUMBER :
- 119006-77-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C22-H16-F2-N2
- MOLECULAR WEIGHT :
- 346.40
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 808 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1079 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
