1,1,3,3-Tetramethylguanidine

物化性质

外观与性状：

透明液体

密度：

0.90±0.1 g/cm3

熔点：

-30 °C

沸点：

163.2±9.0 °C

闪点：

60.0±0.0 °C

水溶解性：

Very Soluble (147 g/L)

折射率：

n20/D 1.469

蒸汽密度：

2.09 Torr

存储条件/存储方法：

其它信息：

1.性状：无色透明液体。

2.密度（g/mL,25/4℃）：0.915

3.相对蒸汽密度（g/mL,空气=1）：不确定

4.熔点（ºC）：不确定

5.沸点（ºC,常压）：159-160

四甲基胍 安全信息

包装等级：

II

风险类别：

8

海关代码：

2942000000

WGK_Germany：

1
德国有关水污染物质的分类清单

危险类别码：

R10;R20/22;R34

安全说明：

S26-S27-S36/37/39-S45-S16

安全标志：

S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S27:立刻除去所有污染衣物。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。
:

危险标志：

C:Corrosive;

安全信息

外观与性状：

透明液体

密度：

0.90±0.1 g/cm3

熔点：

-30 °C

沸点：

163.2±9.0 °C

闪点：

60.0±0.0 °C

水溶解性：

Very Soluble (147 g/L)

折射率：

n20/D 1.469

蒸汽密度：

2.09 Torr

存储条件/存储方法：

其它信息：

1.性状：无色透明液体。

2.密度（g/mL,25/4℃）：0.915

3.相对蒸汽密度（g/mL,空气=1）：不确定

4.熔点（ºC）：不确定

5.沸点（ºC,常压）：159-160

四甲基胍 安全信息

包装等级：

II

风险类别：

8

海关代码：

2942000000

WGK_Germany：

1
德国有关水污染物质的分类清单

危险类别码：

R10;R20/22;R34

安全说明：

S26-S27-S36/37/39-S45-S16

安全标志：

S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S27:立刻除去所有污染衣物。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。
:

危险标志：

C:Corrosive;

MSDS

Name:	1 1 3 3-Tetramethylguanidine 99% (gc) Material Safety Data Sheet
Synonym:	Non
CAS:	80-70-6

Section 1 - Chemical Product   MSDS Name:1 1 3 3-Tetramethylguanidine 99% (gc) Material Safety Data Sheet
Synonym:Non
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
80-70-6	1,1,3,3-Tetramethylguanidine	99%	201-302-7

Hazard Symbols: C
Risk Phrases: 34
Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat as a caustic agent.
Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Section 7 - HANDLING and STORAGE
  Handling:
Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 80-70-6: Personal Protective Equipment Eyes: Wear chemical goggles and a face shield if splashing is possible.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: Not available.
Odor: Mild ammoniacal odor
pH: Not available.
Vapor Pressure: .26 hPa @ 25 deg C
Viscosity: mPas 20 deg C
Boiling Point: 160 - 162 deg C @ 760.00mm Hg
Freezing/Melting Point: <-30 deg C
Autoignition Temperature: 350 deg C ( 662.00 deg F)
Flash Point: 60 deg C ( 140.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: miscible with water
Specific Gravity/Density: .9180g/cm3
Molecular Formula: C5H13N3
Molecular Weight: 115.18
Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents - strong acids - acid chlorides - acid anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 80-70-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1,1,3,3-Tetramethylguanidine - Not listed by ACGIH, IARC, or NTP.
Section 12 - ECOLOGICAL INFORMATION
 
Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.*
Hazard Class: 8 (3)
UN Number: 2920
Packing Group: II
IMO
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.
Hazard Class: 8 (3)
UN Number: 2920
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.
Hazard Class: 8
UN Number: 2920
Packing group: II
Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 25 Avoid contact with eyes.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 80-70-6: 2
Canada
CAS# 80-70-6 is listed on Canada's DSL List.
CAS# 80-70-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 80-70-6 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：34.66

2、摩尔体积（m³/mol）：127.5

3、等张比容（90.2K）：292.7

4、表面张力（dyne/cm）：27.7

5、极化率（10^-24cm³）：13.74

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:1

4.可旋转化学键数量:2

5.互变异构体数量:无

6.拓扑分子极性表面积30.3

7.重原子数量:8

8.表面电荷:0

9.复杂度:75.7

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1