uranyl nitrate hexahydrate

物化性质

外观与性状：

淡黄色结晶固体

密度：

2,807 g/cm3

熔点：

60,2°C

沸点：

83ºC at 760 mmHg

蒸汽压：

49.8mmHg at 25°C

稳定性相关：

六水合硝酸铀酰为黄色结晶，发黄绿色的荧光。熔点为60℃。在干燥空气中慢慢脱水，在潮湿空气中可潮解。可溶于乙醇、丙酮和乙醚。

安全信息

外观与性状：

淡黄色结晶固体

密度：

2,807 g/cm3

熔点：

60,2°C

沸点：

83ºC at 760 mmHg

蒸汽压：

49.8mmHg at 25°C

稳定性相关：

六水合硝酸铀酰为黄色结晶，发黄绿色的荧光。熔点为60℃。在干燥空气中慢慢脱水，在潮湿空气中可潮解。可溶于乙醇、丙酮和乙醚。

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

YR3850000

CHEMICAL NAME :

Uranium, bis(nitrato)dioxo-, hexahydrate

CAS REGISTRY NUMBER :

13520-83-7

LAST UPDATED :

199806

DATA ITEMS CITED :

29

MOLECULAR FORMULA :

N2-O8-U.6H2-O

MOLECULAR WEIGHT :

502.14

WISWESSER LINE NOTATION :

ONO&O-UR-O&O&ONO &QH 6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

135 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

12 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

6750 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

238 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

630 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Bird - chicken

DOSE/DURATION :

299 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Liver - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

200 mg/kg/29W-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - hamster Lung

DOSE/DURATION :

180 mg/L

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 85,288,1981 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(U)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,274,1971 OSHA PEL (Gen Indu):8H TWA 0.05 mg(U)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.2 mg(U)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.05 mg(U)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.05 mg(U)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg(U)/m3;STEL 0.5 mg(U)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993 OEL-DENMARK:TWA 0.2 mg(U)/m3 JAN 1993 OEL-FINLAND:TWA 0.2 mg(U)/m3 JAN 1993 OEL-GERMANY:TWA 0.25 mg(U)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 mg(U)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.05 mg(U)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.25 mg(U)/m3 JAN 1993 OEL-POLAND:TWA 0.015 mg(U)/m3 JAN 1993 OEL-POLAND:TWA 0.075 mg(U)/m3 JAN 1993 OEL-RUSSIA:STEL 0.015 mg(U)/m3 JAN 1993 OEL-RUSSIA:STEL 0.075 mg(U)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.2 mg(U)/m3 JAN 1993 OEL-TURKEY:TWA 0.05 mg(U)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993

MSDS

Section 1. Chemical Product and Company Identification
Uranyl nitrate hexahydrate
Common Name/
Trade Name
Uranyl nitrate hexahydrate
Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. Flush with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Cold water may be used. Get medical attention. Seek medical attention
in case of eye contact with a radioactive material.
Skin ContactIn case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.
Remove contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention.
Serious Skin Contact
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical
attention in case of skin contact with a radioactive material.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious InhalationEvacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. If breathing is difficult, administer oxygen. If the victim is not breathing, perform
mouth-to-mouth resuscitation. Seek medical attention in case of inhalation of a radioactive material.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.
Section 5. Fire and Explosion Data
Flammability of the Product Non-flammable.
Auto-Ignition Temperature Not applicable.
Flash PointsNot applicable.
Flammable LimitsNot applicable.
Hazardous decompostion products include UO2, UO3, U3O8, NOx (thermal, alpha, beta, gamma radiation,
Products of Combustion
uranium daughters (decay).
Fire Hazards in Presence ofof combustible materials of organic materials
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of static discharge, sparks, open flames, heat: Not available.
of Various SubstancesRisks of explosion of the product in presence of mechanical impact: Not available.
Fire Fighting MediaNot applicable.
and Instructions
Special Remarks onThis material is an oxidizer. It may enhance combustion of other materials.
Fire Hazards
Special Remarks on Explosion Solutions of uranyl nitrate hexahydrate in ether should not be allowed to stand in sunlight as explosion may
Hazardsoccur.
Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container.
Large SpillRadioactive material. Oxidizing material.
Stop leak if without risk. Do not attempt recovery actions unless for rescue purposes. Do not touch damaged
container or spilled material. Do not clean-up or dispose except under supervision of a specialist. Avoid
contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray.
for assistance on disposal. Be careful that the product is not present at a concentration level above TLV.
Check TLV on the MSDS and with local authorities.
Uranyl nitrate hexahydrate
Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Keep away from combustible material.. Do not
breathe dust. Take precautionary measures against electrostatic discharges. Wear suitable protective
clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical
advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from
incompatibles such as reducing agents, organic materials, metals.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Separate from acids, alkalies,
reducing agents and combustibles. See NFPA 43A, Code for the Storage of Liquid and Solid Oxidizers.
Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spill
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
TWA: 0.25 (mg/m3) from OSHA (PEL) [United States]
Exposure Limits
TWA: 0.05 (mg(U)/m3) from OSHA (PEL) [United States]
TWA: 0.2 STEL: 0.6 (mg/m3) [United Kingdom (UK)]
TWA: 0.2 (mg/m3) [Australia]
TWA: 0.2 STEL: 0.6 (mg/m3) [Canada]
Consult local authorities for acceptable exposure limits.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Deliquescent crystals solid.)OdorOdorless.
TasteNot available.
Molecular Weight502.13 g/mole
ColorYellow.
pH (1% soln/water)Not available.
Decomposition temperature: 118°C (244.4°F)
Boiling Point
Melting Point60.2°C (140.4°F)
Critical TemperatureNot available.
Specific Gravity2.807 (Water = 1)
Vapor PressureNot applicable.
Vapor DensityNot available.
VolatilityNot available.
Not available.
Odor Threshold
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water, methanol, diethyl ether, acetone.
SolubilityEasily soluble in cold water, hot water, methanol, acetone.
Soluble in diethyl ether.
Soluble in mineral acids, alkalies, oxalates.
Very soluble in acetic acid.
Solubility in water: 8 g/l of water @ 14 deg. C; 33 g/l of water @ 100 deg. C; 127 g/100 g@25 deg. C.
Uranyl nitrate hexahydrate
Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Conditions of InstabilityIncompatible materials
Incompatibility with variousReactive with reducing agents, combustible materials, organic materials.
substances
Non-corrosive in presence of glass.
Corrosivity
Special Remarks onThis material is an oxidizer. It may enhance combustion of other materials.
ReactivityIt emits radioactive and toxic (NOx) fumes when heated to decompositon.
It is also incompatible with cellulose, diethyl ether (ether solutions) and organic solvents.
When dissolved in water, a weak solution of nitric acid forms. Water solutions are acidic and can corrode
Special Remarks on
Corrosivitymetals.
PolymerizationWill not occur.
Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on HumansCARCINOGENIC EFFECTS: Classified A1 (Confirmed for human.) by ACGIH. Classified 2A (Probable for
human.) by IARC.
May cause damage to the following organs: blood, kidneys, lungs, liver, bone marrow.R68-
Other Toxic Effects onHazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Special Remarks onLowest Published Lethal Dose:
Toxicity to AnimalsLDL [Dog] - Route: Oral; Dose: 12 mg/kg
LDL[Cat] - Route: Oral; Dose: 238 mg/kg
Lethal Dose/Conc. 50% kill:
LD50[Rat] - Route: Intraperitoneal; Dose: 135 mg/kg
LD50[Chicken] - Route: Subcutaneous; Dose: 299 mg/kg
Special Remarks onMay cause cancer.
Chronic Effects on HumansMay affect genetic material (mutagenic).
Special Remarks on otherIt is a radioactive material (low level radioactivity)
Toxic Effects on HumansAcute/Chronic Potential Health Effects:
Skin: Causes skin irritation and possible ulceration.
Eyes: Causes eye irritation and possible conjunctivitis. Risk of serious injury possible.
Inhalation: Causes irritation of the respiratory and mucous membranes. It is slightly corrosive to the
respiratory (mucous) membranes. Symptoms may include coughing fits, sneezing, difficulty breathing,
burning sensation, acute aterial lesions, and pulmonary edema. It is transferred from the lungs of animals
quite slowly. A suspect carcinogen. Chronic exposure by inhalation may cause lung cancer, and kidney
damage.
Ingestion: Causes gastrointestinal tract irritation. Symptoms may include salivation, burning sensation in the
stomach, cramps, nausea, vomiting, weakness, dizziness, diarrhea, convulsions, flushed skin, sweating,
syncope, tachycardia, hypotension and state of shock possible. Being radioactive, this compound is
carcinogenic at any site of contamination on the body. Acute or chronic exposure may cause liver and kidney
damage, and blood/bone marrow changes. Chronic exposure may also affect metabolism (weight loss).
Addtional Data Concerning Uranyl Nitate:
Uranium is a highly toxic element on an acute basis. The levels for soluble compounds are based on the
chemical toxicity while the permissible body level for insoluble compounds is based on radioactivity.
Uranyl nitrate hexahydrate
Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products
may arise.
Toxicity of the ProductsThe product itself and its products of degradation are not toxic.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation
Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.
Section 14. Transport Information
DOT ClassificationCLASS 5.1: Oxidizing material.
UNNA: 1477 : Nitrate, inorganic, n.o.s (Uranyl Nitrate) PG: III
Identification
Special Provisions forNot available.
Transport
DOT (Pictograms)
OXIDIZER
5.1
Section 15. Other Regulatory Information and Pictograms
Pennsylvania RTK: Uranyl nitrate hexahydrate
Federal and State
Minnesota: Uranyl nitrate hexahydrate (Listed as Uraniun soluble compounds)
Regulations
New Jersey: Uranyl nitrate hexahydrate
California Director's List of Hazardous Substances: Uranyl nitrate hexahydrate (Listed as Uranium
compounds)
California prop. 65: This product contains the following ingredients for which the State of California has
California
found to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
China: Listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Listed on National Inventory (PICCS).
Australia: Listed on AICS.
The classification of this product has not been validated yet the the Service du
Other ClassificationsWHMIS (Canada)
repertoire toxicologique. However, it might be classified as follows: CLASS C:
Oxidizing material.
DSCL (EEC)R8- Contact with combustibleS20/21- When using do not eat, drink or
material may cause fire.smoke.
R26/28- Very toxic by inhalation andS26- In case of contact with eyes, rinse
if swallowed.immediately with plenty of water and seek
R33- Danger of cumulative effects.medical advice.
R36/38- Irritating to eyes and skin.S36/37- Wear suitable protective clothing and
R51/53- Toxic to aquatic organisms,gloves.
may cause long-term adverse effectsS45- In case of accident or if you feel unwell,
Uranyl nitrate hexahydrate
in the aquatic environment.seek medical advice immediately (show the
label where possible).
S61- Avoid release to the environment. Refer
to special instructions/Safety data sheets.
Health Hazard
HMIS (U.S.A.)2 National Fire Protection
0 Flammability
0 Association (U.S.A.)
Fire Hazard
2 1 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
x
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate
respirator when ventilation is
inadequate.
Splash goggles.
SECTION 16 - ADDITIONAL INFORMATION
N/A