demethyl-coclaurine
- 中文别名：去甲乌药碱
- 中文释义：去甲基衡州乌药碱;去甲乌药碱
- 英文别名：(RS)-norcoclaurine;
Coclaurine,O-demethyl-,(+-);
1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol;
1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;
Norcoclaurine;
(+-)-Demethylcoclaurine;
(+-)-O-Demethylcoclaurine;
1-(p-hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline;
(R,S)-norcoclaurine;
rac-norcoclaurine;
6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-,(+-);
Higenamine
- CAS No.：5843-65-2
- 分子式：
C16H17NO3
- 分子量：271.31
- 精确分子量：271.12100
- PSA：72.72000
- InChI：InChI=1/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
- 分子结构式：
物化性质
- 密度：
- 1.317g/cm3
- 沸点：
- 522.4ºC at 760mmHg
- 闪点：
- 209.6ºC
- 折射率：
- 1.666
- 存储条件/存储方法：
- 库房低温,通风,干燥
安全信息
- 密度：
- 1.317g/cm3
- 沸点：
- 522.4ºC at 760mmHg
- 闪点：
- 209.6ºC
- 折射率：
- 1.666
- 存储条件/存储方法：
- 库房低温,通风,干燥
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GG5370000
- CHEMICAL NAME :
- Coclaurine, O-demethyl-, (+-)-
- CAS REGISTRY NUMBER :
- 5843-65-2
- LAST UPDATED :
- 199503
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H17-N-O3
- MOLECULAR WEIGHT :
- 271.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
热门化工词典词汇
- 1,1'-(1,3-Propanediyl)bis[1,1-bis(2-methoxy-5-methylphenyl)phosphine]1,1'-(1,3-丙二基)双[1,1-双(2-甲氧基-5-甲基苯基)膦]
- dimethyl bicyclo[2.2.1]heptane-2,3-dicarboxylatedimethyl bicyclo[2.2.1]heptane-2,3-dicarboxylate
- 4-(6-Methoxy-pyriMidin-4-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester4-(6-甲氧基-嘧啶-4-基氨基)-哌啶-1-羧酸叔丁基酯
- 2-Propenoicacid,2-hydroxyethylester,polymerwith.alpha.-hydro-.omega.-hydroxypoly(oxy-1,4-butanediyl)and1,1-methylenebis[42-丙烯酸-2-羟乙基酯与&alpha
- 3-Pyridinemethanol,5,6-dichloro-5,6-二氯-3-嘧啶甲醇
- 5-(1-ethyl-5-methylpyrazol-4-yl)-1,2-oxazole-3-carboxylic acid5-(1-乙基-5-甲基-1H-吡唑-4-基)-异恶唑-3-羧酸
- 5-methylsulfonylthiophene-2-carbaldehyde5-(甲基磺酰基)-2-噻吩甲醛
- 1-bromo-6-methylcyclohexene1-溴-6-甲基环己烯
- 2,4,6(1H,3H,5H)-Pyrimidinetrione,5-methyl-5-METHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
- 3,4-dibromonaphthalene-1,2-dione3,4-二溴-1,2-萘二酮
