4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-
- 中文别名：阿地西林
- 中文释义：阿地西林;青黴素N
- 英文别名：penicillin N;
Penicillin;
Synnematin B;
Adicillin;
Cephalosporin N;
(2S,5R,6R)-6-[[(5R)-5-amino-5-carboxy-pentanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
(6R)-6-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]penicillanic acid
- CAS No.：525-94-0
- 分子式：
C14H21N3O6S
- 分子量：359.40
- 精确分子量：359.11500
- PSA：175.33000
- InChI：The Key: MIFYHUACUWQUKT-GPUHXXMPSA-N
- 分子结构式：
物化性质
- 密度：
- 1.5g/cm3
- 沸点：
- 739.2ºC at 760mmHg
- 闪点：
- 400.9ºC
- 折射率：
- 1.632
安全信息
- 密度：
- 1.5g/cm3
- 沸点：
- 739.2ºC at 760mmHg
- 闪点：
- 400.9ºC
- 折射率：
- 1.632
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH8213500
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(5-amino-5-carboxyvaleramido)-3,3- dimethyl-7-oxo-, D-
- CAS REGISTRY NUMBER :
- 525-94-0
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H21-N3-O6-S
- MOLECULAR WEIGHT :
- 359.44
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CZ CMV4VQ F1 F1 GVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),93,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),93,1980 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993
