vat yellow 4

物化性质

外观与性状：

黏的橙色液体

密度：

1.418 g/cm3

沸点：

606.7ºC at 760 mmHg

闪点：

219.9ºC

折射率：

1.792

蒸汽压：

1.15E-14mmHg at 25°C

稳定性相关：

黄色粉状，不溶于水，溶于二甲苯、硝基苯和四氢化萘，微溶于丙酮、乙醇、苯、氯仿、甲苯、吡啶、邻氯苯酚。在浓硫酸中呈红光青莲色，稀释后成橙色沉淀。在碱性保佑险粉还原液中呈枣红色，在酸性液中呈金黄色。属蒽醌系还原染料。具有严重光脆性。

安全信息

外观与性状：

黏的橙色液体

密度：

1.418 g/cm3

沸点：

606.7ºC at 760 mmHg

闪点：

219.9ºC

折射率：

1.792

蒸汽压：

1.15E-14mmHg at 25°C

稳定性相关：

黄色粉状，不溶于水，溶于二甲苯、硝基苯和四氢化萘，微溶于丙酮、乙醇、苯、氯仿、甲苯、吡啶、邻氯苯酚。在浓硫酸中呈红光青莲色，稀释后成橙色沉淀。在碱性保佑险粉还原液中呈枣红色，在酸性液中呈金黄色。属蒽醌系还原染料。具有严重光脆性。

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

HO7030000

CHEMICAL NAME :

Dibenzo(b,def)chrysene-7,14-dione

CAS REGISTRY NUMBER :

128-66-5

BEILSTEIN REFERENCE NO. :

2000679

LAST UPDATED :

199712

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C24-H12-O2

MOLECULAR WEIGHT :

332.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5750 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(4),54,1983

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2270 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(4),54,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

79500 mg/kg/6W-I

TOXIC EFFECTS :

Liver - liver function tests impaired Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(4),54,1983 ** TUMORIGENIC DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

7420 gm/kg/2Y-C

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease

REFERENCE :

NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-134,1979

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2225 gm/kg/106W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease

REFERENCE :

NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-134,1979 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,161,1990 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,161,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,161,1990

海关数据

中国海关编码：2914399090

概述：

2914399090. 其他不含其他含氧基的芳香酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 丙酮报明包装

摘要/Summary：

2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

分子结构与计算化学数据

分子结构数据

1、 摩尔折射率：99.44

2、 摩尔体积（cm³/mol）：234.3

3、 等张比容（90.2K）：678.7

4、 表面张力（dyne/cm）：70.3

5、 极化率（10-24cm3）：39.42

计算化学数据

1.疏水参数计算参考值（XlogP）:5.4

2.氢键供体数量:0

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积34.1

7.重原子数量:26

8.表面电荷:0

9.复杂度:570

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1