8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-methyl-, (3-endo)-
- 中文别名：苯甲托品
- 中文释义：苯甲托品
- 英文别名：benzatropine;
Benaztropine;
benzotropine;
exo-Benztropine;
tropine benzohydryl ether
- CAS No.：86-13-5
- 分子式：
C21H25NO
- 分子量：307.43
- 精确分子量：307.19400
- PSA：12.47000
- InChI：The Key: GIJXKZJWITVLHI-PMOLBWCYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.11g/cm3
- 沸点：
- 409ºC at 760 mmHg
- 闪点：
- 120.1ºC
- 折射率：
- 1.604
- 存储条件/存储方法：
- 通风低温干燥,与库房食品原料分开存放
安全信息
- 密度：
- 1.11g/cm3
- 沸点：
- 409ºC at 760 mmHg
- 闪点：
- 120.1ºC
- 折射率：
- 1.604
- 存储条件/存储方法：
- 通风低温干燥,与库房食品原料分开存放
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM3100000
- CHEMICAL NAME :
- 1-alpha-H,5-alpha-H-Tropane, 3-alpha-(diphenylmethoxy)-
- CAS REGISTRY NUMBER :
- 86-13-5
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H25-N-O
- MOLECULAR WEIGHT :
- 307.47
- WISWESSER LINE NOTATION :
- T56 A ANTJ A1 GOYR&R -ALL ALPHA
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,215,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,215,1961 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3957 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 103 (estimated) No. of Female Employees: 52 (estimated)
