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moricizine hydrochloride

moricizine hydrochloride


  • 中文别名:盐酸莫雷西嗪
  • 中文释义:盐酸莫雷西嗪;1,3-Dichloro-2,2-dimethylpropane;Dimethyldichloropropane;4\'-Bromo[1,1\'-biphenyl]-4-ol;4\'-Bromobiphenyl-4-ol;4-Bromo-4\'-hydroxybiphenyl;Thiosulfuric acid, S,S\'-(2-(dimethylamino)trimethylene)ester, monosodium salt;Thiosulfuric acid,S,S\'-[2-(dim
  • 英文别名:moricizine hydrochloride;
    Moracizin-HCl;
    ethmozoine hydrochloride;
    Etmozin;
    Moricizine HCl;
    Ethmosine;
    UNII-71OK3Z1ESP;
    Ethmozin;
    ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate,hydrochloride;
    Moracizine hydrochloride;
    EN 313;
    MORICIZINE HYDROCHLORIDE;
    Ethmozine 
  • CAS No.:29560-58-5
  • 分子式:

    C22H26ClN3O4S

  • 分子量:463.97800
  • 精确分子量:463.13300
  • PSA:96.41000
  • InChI:InChI=1/C22H25N3O4S.ClH/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24;/h3-8,15H,2,9-14H2,1H3,(H,23,27);1H
  • 分子结构式:

物化性质

外观与性状:
白色至黄褐色的结晶粉末
沸点:
625ºC at 760 mmHg
闪点:
331.8ºC
蒸汽压:
1.54E-15mmHg at 25°C

安全信息

外观与性状:
白色至黄褐色的结晶粉末
沸点:
625ºC at 760 mmHg
闪点:
331.8ºC
蒸汽压:
1.54E-15mmHg at 25°C

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN6500000
CHEMICAL NAME :
Phenothiazine-2-carbamic acid, 10-(3-morpholinopropionyl)-, ethyl ester, hydrochloride
CAS REGISTRY NUMBER :
29560-58-5
LAST UPDATED :
199803
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C22-H25-N3-O4-S.Cl-H
MOLECULAR WEIGHT :
464.02
WISWESSER LINE NOTATION :
T C666 BN ISJ EMVO2 B2V- AT6N DOTJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 53(3),30,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 48(1),60,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 53(3),30,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
131 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,74,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
31 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,640,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 48(5),43,1985

海关数据

中国海关编码:2934999090

概述:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途
摘要/Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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