2-Pyrrolidinone,1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-
- 中文别名：多沙普仑
- 中文释义：多沙普仑;1-乙基-4-(2-吗啉-4-乙基)-3,3-二苯基-2-吡咯烷酮;吗乙苯吡酮
- 英文别名：doxapram;
Doxapramum;
1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;
Dopram;
doxapram hydrochloride;
Doxapram HCL
- CAS No.：309-29-5
- 分子式：C24H30N2O2
- 分子量：378.51
- 精确分子量：378.23100
- PSA：32.78000
- InChI：InChI=1/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8
- 分子结构式：
物化性质
- 密度：
- 1.104 g/cm3
- 沸点：
- 536.4ºC at 760 mmHg
- 闪点：
- 278.2ºC
- 折射率：
- 1.562
安全信息
- 密度：
- 1.104 g/cm3
- 沸点：
- 536.4ºC at 760 mmHg
- 闪点：
- 278.2ºC
- 折射率：
- 1.562
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY5769500
- CHEMICAL NAME :
- 2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-
- CAS REGISTRY NUMBER :
- 309-29-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H30-N2-O2
- MOLECULAR WEIGHT :
- 378.56
- WISWESSER LINE NOTATION :
- T6N DOTJ A2- DT5NVTJ A2 CR& CR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 268 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 30,522,1978 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 1800 ug/kg
- SEX/DURATION :
- female 16 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - other effects to embryo
- REFERENCE :
- BJOGAS British Journal of Obstetrics and Gynaecology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.82- 1975- Volume(issue)/page/year: 84,48,1977
海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
