dichlorine

物化性质

外观与性状：

淡绿色-黄色气体带有一种刺激的气味

密度：

1.468（0℃）

熔点：

−101 °C(lit.)

沸点：

−34 °C(lit.)

水溶解性：

0.7 g/100 mL

折射率：

1.375

蒸汽密度：

2.48 (vs air)

存储条件/存储方法：

库房通风低温干燥,轻装轻卸,与易燃气体、氨、金属粉末分开储运

稳定性相关：

1.具有窒息的气味，有强烈刺激臭和腐蚀性。性质很活泼，虽不自燃，但可以助燃，在日光下与其他易燃气体混合时会发生燃烧和爆炸，可以和大多数元素或化合物起反应。剧毒。在0℃，599986Pa下凝结为金黄色液体，20℃，100mL水中能溶解氯0.7291g，液氯相对密度1.557（-34℃），2.13（-195℃）。化学性质活泼，几乎与所有元素都能发生作用。

2.稳定性^[16] 稳定

3.禁配物^[17]易燃或可燃物、烷烃、炔烃、卤代烷烃、芳香烃、胺类、醇类、乙醚、氢、金属、苛性碱、非金属单质、非金属氧化物、金属氢化物等

4.聚合危害^[18] 不聚合

其它信息：

1.性状：黄绿色、有刺激性气味的气体。^[1]

2.熔点（℃）：-101^[2]

3.沸点（℃）：-34.0^[3]

4.相对密度（水=1）：1.41（20℃）^[4]

5.相对蒸气密度（空气=1）：2.5^[5]

6.饱和蒸气压（kPa）：673（20℃）^[6]

7.临界温度（℃）：144^[7]

8.临界压力（MPa）：7.71^[8]

9.辛醇/水分配系数：0.85^[9]

10.溶解性：微溶于冷水，溶于碱、氯化物和醇类。^[10]

安全信息

外观与性状：

淡绿色-黄色气体带有一种刺激的气味

密度：

1.468（0℃）

熔点：

−101 °C(lit.)

沸点：

−34 °C(lit.)

水溶解性：

0.7 g/100 mL

折射率：

1.375

蒸汽密度：

2.48 (vs air)

存储条件/存储方法：

库房通风低温干燥,轻装轻卸,与易燃气体、氨、金属粉末分开储运

稳定性相关：

1.具有窒息的气味，有强烈刺激臭和腐蚀性。性质很活泼，虽不自燃，但可以助燃，在日光下与其他易燃气体混合时会发生燃烧和爆炸，可以和大多数元素或化合物起反应。剧毒。在0℃，599986Pa下凝结为金黄色液体，20℃，100mL水中能溶解氯0.7291g，液氯相对密度1.557（-34℃），2.13（-195℃）。化学性质活泼，几乎与所有元素都能发生作用。

2.稳定性^[16] 稳定

3.禁配物^[17]易燃或可燃物、烷烃、炔烃、卤代烷烃、芳香烃、胺类、醇类、乙醚、氢、金属、苛性碱、非金属单质、非金属氧化物、金属氢化物等

4.聚合危害^[18] 不聚合

其它信息：

1.性状：黄绿色、有刺激性气味的气体。^[1]

2.熔点（℃）：-101^[2]

3.沸点（℃）：-34.0^[3]

4.相对密度（水=1）：1.41（20℃）^[4]

5.相对蒸气密度（空气=1）：2.5^[5]

6.饱和蒸气压（kPa）：673（20℃）^[6]

7.临界温度（℃）：144^[7]

8.临界压力（MPa）：7.71^[8]

9.辛醇/水分配系数：0.85^[9]

10.溶解性：微溶于冷水，溶于碱、氯化物和醇类。^[10]

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

FO2100000

CHEMICAL NAME :

Chlorine

CAS REGISTRY NUMBER :

7782-50-5

LAST UPDATED :

199712

DATA ITEMS CITED :

63

MOLECULAR FORMULA :

Cl2

MOLECULAR WEIGHT :

70.90

WISWESSER LINE NOTATION :

G2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human

DOSE/DURATION :

2530 mg/m3/30M

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - emphysema Lungs, Thorax, or Respiration - chronic pulmonary edema

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human

DOSE/DURATION :

500 ppm/5M

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

293 ppm/1H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

137 ppm/1H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

800 ppm/30M

TOXIC EFFECTS :

Behavioral - muscle weakness Gastrointestinal - nausea or vomiting Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

3200 ppm/3H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

500 ppm/5M

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

3312 mg/kg/92D-C

TOXIC EFFECTS :

Blood - change in clotting factors

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

109 gm/kg/2Y-C

TOXIC EFFECTS :

Endocrine - changes in spleen weight Blood - changes in other cell count (unspecified) Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9 ppm/6H/6W-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

7568 mg/kg/28D-C

TOXIC EFFECTS :

Behavioral - food intake (animal) Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

42 gm/kg/2W-C

TOXIC EFFECTS :

Brain and Coverings - changes in brain weight Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9100 ppb/6H/5D-I

TOXIC EFFECTS :

Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

153 gm/kg/73W-C

TOXIC EFFECTS :

Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - changes in ovarian weight

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

9100 ppb/6H/5D-I

TOXIC EFFECTS :

Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5096 mg/kg/2Y-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

565 mg/kg

SEX/DURATION :

male 8 week(s) pre-mating female 2 week(s) pre-mating - 3 week(s) post-birth

TOXIC EFFECTS :

Reproductive - Effects on Newborn - biochemical and metabolic

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

REFERENCE :

ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,201,1985 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-STEL 2.9 mg/m3 (1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 1.5 mg/m3 (0.5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 1 ppm (3 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,46,1971 OSHA PEL (Gen Indu):CL 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 1 ppm (3 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 0.5 ppm (1.5 mg/m3) JAN 1993 OEL-BELGIUM:TWA 0.5 ppm (1.5 mg/m3);STEL 1 ppm (3 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.5 ppm (1.5 mg/m3) JAN 1993 OEL-FINLAND:TWA 0.5 ppm (1.5 mg/m3);STEL 1 ppm (3 mg/m3) JAN 1993 OEL-FRANCE:STEL 1 ppm (3 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.5 ppm (1.5 mg/m3) JAN 1993 OEL-HUNGARY:STEL 1 mg/m3 JAN 1993 OEL-INDIA:TWA 1 ppm (3 mg/m3);STEL 3 ppm (9 mg/m3) JAN 1993 OEL-JAPAN:TWA 1 ppm (2.9 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-POLAND:TWA 1.5 mg/m3 JAN 1993 OEL-RUSSIA:TWA 1 ppm;STEL 1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.5 ppm (1.5 mg/m3);STEL 1 ppm (3 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.5 ppm (1.5 mg/m3);STEL 1 ppm (3 mg/m3) JAN 1993 OEL-THAILAND:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-TURKEY:TWA 1 ppm (3 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1 ppm (3 mg/m3);STEL 3 ppm (9 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CHLORINE-air:10H TWA 0.5 ppm;STEL 1 ppmREFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 18040 No. of Facilities: 21429 (estimated) No. of Industries: 169 No. of Occupations: 86 No. of Employees: 220544 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9656 No. of Facilities: 338 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 4768 (estimated) No. of Female Employees: 1862 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 18040 No. of Facilities: 5343 (estimated) No. of Industries: 70 No. of Occupations: 75 No. of Employees: 178105 (estimated) No. of Female Employees: 20221 (estimated)

毒理学数据：

1.急性毒性^[11] LC50：850mg/m³（大鼠吸入，1h）

2.刺激性 暂无资料

3.亚急性与慢性毒性^[12] 家兔吸入2~5mg/m³，每天5h，1~9个月，出现消瘦、上呼吸道炎、肺炎、胸膜炎及肺气肿等。大鼠吸入41~97mg/m³，每天1~2h，3~4周，引起严重但非致死性的肺气肿与气管病变。

4.致突变性^[13] 细胞遗传学分析：人淋巴细胞20ppm。精子形态学分析：小鼠经口20mg/kg（5d）（连续）。微生物致突变：鼠伤寒沙门菌1800μg/L。

5.其他^[14] LCLo：2530mg/m³（人吸入30min），500ppm（人吸入5min）

生态数据：

1.生态毒性^[15] LC50：0.44mg/L（96h）（蓝鳃太阳鱼）；0.49mg/L（96h）（水蚤）

2.生物降解性 暂无资料

3.非生物降解性 暂无资料

MSDS

第一部分：化学品名称

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：11.74

2、摩尔体积（cm³/mol）：51.3

3、等张比容（90.2K）：109.0

4、表面张力（dyne/cm）：20.4

5、介电常数：无可用的

6、极化率（10^-24cm³）：4.65

7、单一同位素质量：69.937705 Da

8、标称质量：70 Da

9、平均质量：70.906 Da

计算化学数据

1.疏水参数计算参考值（XlogP）:1.6

2.氢键供体数量:0

3.氢键受体数量:0

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积0

7.重原子数量:2

8.表面电荷:0

9.复杂度:0

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1