1,2-dihydrorotenone
- 中文别名：二氢鱼藤酮
- 中文释义：二氢鱼藤酮
- 英文别名：Dihydrorotenone (VAN);
1',2'-dihydrorotenone;
6'.7'-Dihydro-rotenon;
1-Dihydrorotenon;
Dihydrorotenone;
6',7'-dihydrorotenone
- CAS No.：6659-45-6
- 分子式：
C23H24O6
- 分子量：396.43306
- 精确分子量：396.15700
- PSA：63.22000
- InChI：The Key: DTFARBHXORYQBF-HBGVWJBISA-N
- 分子结构式：
物化性质
- 密度：
- 1.251g/cm3
- 沸点：
- 553.9ºC at 760 mmHg
- 闪点：
- 241.6ºC
- 折射率：
- 1.579
安全信息
- 密度：
- 1.251g/cm3
- 沸点：
- 553.9ºC at 760 mmHg
- 闪点：
- 241.6ºC
- 折射率：
- 1.579
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DJ2623100
- CHEMICAL NAME :
- (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6a-al phah)-one, 1,2,12,12a-alpha-tetrahydro- 2-alpha-isopropyl-8,9-dimethoxy-
- CAS REGISTRY NUMBER :
- 6659-45-6
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C23-H24-O6
- MOLECULAR WEIGHT :
- 396.47
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,364,1953
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IECHAD Industrial and Engineering Chemistry. (Washington, DC) V.15-62, 1923-70. For publisher information, see CHMTBL. Volume(issue)/page/year: 29,429,1937
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- IECHAD Industrial and Engineering Chemistry. (Washington, DC) V.15-62, 1923-70. For publisher information, see CHMTBL. Volume(issue)/page/year: 29,429,1937 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4616 mg/kg/57W-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,364,1953
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