ansamitocin P-3
- 中文别名：安丝菌素
- 中文释义：安丝菌素 P 3;安丝菌素
- 英文别名：ansamitocin P3;
2'-De(acetylmethylamino)-2'-methylmaytansine;
ANSAMITOCIN P-3;
Maytansinol isobutyrate;
(3E,5E,7R,84S)-14-chloro-10t,11c-epoxy-84-hydroxy-12c-isobutyryl-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione;
Anasamitocin P-3;
Ansamitosin P 3;
O3-isobutyryl-maytansinol;
Tam-330
- CAS No.：66584-72-3
- 分子式：C32H43ClN2O9
- 分子量：0
- 精确分子量：634.26600
- PSA：136.16000
- InChI：The Key: OPQNCARIZFLNLF-JBHFWYGFSA-N
- 分子结构式：
物化性质
- 密度：
- 1.29g/cm3
- 熔点：
- 190-192℃
- 沸点：
- 833.1ºC at 760 mmHg
- 闪点：
- 457.7ºC
- 折射率：
- 1.583
安全信息
- 密度：
- 1.29g/cm3
- 熔点：
- 190-192℃
- 沸点：
- 833.1ºC at 760 mmHg
- 闪点：
- 457.7ºC
- 折射率：
- 1.583
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OQ2291000
- CHEMICAL NAME :
- Maytansine, 2'-de(acetylmethylamino)-2'-methyl-
- CAS REGISTRY NUMBER :
- 66584-72-3
- LAST UPDATED :
- 199401
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C32-H43-Cl-N2-O9
- MOLECULAR WEIGHT :
- 635.22
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 625 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 4 ug/kg
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1707,1980
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