potassium cyanide

物化性质

外观与性状：

白色结晶或粉末，易潮解。

密度：

1.00 g/mL at 20 °C

熔点：

634 °C(lit.)

沸点：

1625 °C

闪点：

1625°C

存储条件/存储方法：

Poison room

稳定性相关：

1.在空气中吸收水分和二氧化碳，逐渐分解并放出有苦杏仁气味的氰化氢。在水中溶解后即水解。水溶液在常温下分解较慢，但在高温、光照射以及有氧化剂存在下即氧化。赤热时，与二氧化碳反应，形成一氧化碳及氰酸钾。与镁、铝等金属反应，形成氮化物。水溶液可溶解多种金属而成络合物。熔融物可腐蚀玻璃及石英。剧毒！

2.溶于2份冷水、一份沸水、100份乙醇、25份甲醇。其水溶液呈碱性，并很快分解。在空气中或吸湿逐渐分解。不能燃烧。受高热或与酸接触会产生剧毒的氰化物气体。与硝酸盐、亚硝酸盐、氯酸盐反应剧烈，有发生爆炸的危险。

3.具有极强的毒性，吸入、吞食或者皮肤接触渗透均会致死；暴露在空气中会导致人恶心、晕眩、头疼和气喘,操作时要十分小心，应该在通风橱中进行。使用该试剂时应小心，不要碰到水，因为它接触水后分解生成HCN毒性气体。该试剂跟氯酸盐、硝酸盐、三氯化氮和氨水混合会形成爆炸性的混合物。

4.稳定性^[21] 稳定

5.禁配物^[22] 强氧化剂、酸类

6.避免接触的条件^[23] 潮湿空气

7.聚合危害^[24]不聚合

其它信息：

1.性状：白色结晶或粉末，易潮解。^[12]

2.pH值：11（0.1mol/L水溶液）^[13]

3.熔点（℃）：634.5^[14]

4.相对密度（水=1）：1.52^[15]

5.辛醇/水分配系数：-1.69^[16]

6.溶解性：易溶于水、乙醇、甘油，微溶于甲醇、氢氧化钠水溶液。^[17]

安全信息

外观与性状：

白色结晶或粉末，易潮解。

密度：

1.00 g/mL at 20 °C

熔点：

634 °C(lit.)

沸点：

1625 °C

闪点：

1625°C

存储条件/存储方法：

Poison room

稳定性相关：

1.在空气中吸收水分和二氧化碳，逐渐分解并放出有苦杏仁气味的氰化氢。在水中溶解后即水解。水溶液在常温下分解较慢，但在高温、光照射以及有氧化剂存在下即氧化。赤热时，与二氧化碳反应，形成一氧化碳及氰酸钾。与镁、铝等金属反应，形成氮化物。水溶液可溶解多种金属而成络合物。熔融物可腐蚀玻璃及石英。剧毒！

2.溶于2份冷水、一份沸水、100份乙醇、25份甲醇。其水溶液呈碱性，并很快分解。在空气中或吸湿逐渐分解。不能燃烧。受高热或与酸接触会产生剧毒的氰化物气体。与硝酸盐、亚硝酸盐、氯酸盐反应剧烈，有发生爆炸的危险。

3.具有极强的毒性，吸入、吞食或者皮肤接触渗透均会致死；暴露在空气中会导致人恶心、晕眩、头疼和气喘,操作时要十分小心，应该在通风橱中进行。使用该试剂时应小心，不要碰到水，因为它接触水后分解生成HCN毒性气体。该试剂跟氯酸盐、硝酸盐、三氯化氮和氨水混合会形成爆炸性的混合物。

4.稳定性^[21] 稳定

5.禁配物^[22] 强氧化剂、酸类

6.避免接触的条件^[23] 潮湿空气

7.聚合危害^[24]不聚合

其它信息：

1.性状：白色结晶或粉末，易潮解。^[12]

2.pH值：11（0.1mol/L水溶液）^[13]

3.熔点（℃）：634.5^[14]

4.相对密度（水=1）：1.52^[15]

5.辛醇/水分配系数：-1.69^[16]

6.溶解性：易溶于水、乙醇、甘油，微溶于甲醇、氢氧化钠水溶液。^[17]

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TS8750000

CHEMICAL NAME :

Potassium cyanide

CAS REGISTRY NUMBER :

151-50-8

BEILSTEIN REFERENCE NO. :

4652394

LAST UPDATED :

199806

DATA ITEMS CITED :

55

MOLECULAR FORMULA :

C-K-N

MOLECULAR WEIGHT :

65.12

WISWESSER LINE NOTATION :

KA CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate increase, without fall in BP Vascular - BP lowering not characterized in autonomic section

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human

DOSE/DURATION :

2857 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

13699 ug/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Behavioral - coma Nutritional and Gross Metabolic - metabolic acidosis

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

7814 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

3600 ug/kg

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

8 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

8500 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

5991 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

6500 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2600 ug/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

6 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

2200 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

3972 ug/kg

TOXIC EFFECTS :

Blood - other changes

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

4 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

3256 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Ocular

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

7870 ug/kg

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

8 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

8 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraarterial

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Bird - pigeon

DOSE/DURATION :

4 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Amphibian - frog

DOSE/DURATION :

60 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

31500 mg/kg/50W-C

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes in urine composition Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

14420 mg/kg/13W-C

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - fluid intake Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

72 mg/kg/12D-I

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

84 mg/kg/7D-I

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - rigidity (including catalepsy) Biochemical - Neurotransmitters or modulators (putative) - dopamine in striatum

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

45 gm/kg/6W-I

TOXIC EFFECTS :

Gastrointestinal - other changes Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

65 gm/kg

SEX/DURATION :

female 14 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - other measures of fertility

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

45 mg/kg

SEX/DURATION :

female 1-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1767 mg/kg

SEX/DURATION :

female 8-20 week(s) after conception lactating female 44 day(s) post-birth

TOXIC EFFECTS :

Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - other neonatal measures or effects

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - mouse Mammary gland

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,221,1979 *** REVIEWS *** ACGIH TLV-CL 5 mg(Cn)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW FNSCA6 Forensic Science. (Lausanne, Switzerland) V.1-11, 1972-78. For pub lisher information, see FSINDR. Volume(issue)/page/year: 2,67,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 OSHA PEL (Shipyard):8H TWA 5 mg(CN)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 mg(CN)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 5 mg/m3;STEL 10 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CYANIDE-air:CL 4.7 ppm(CN)/10MREFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 60400 No. of Facilities: 2204 (estimated) No. of Industries: 45 No. of Occupations: 30 No. of Employees: 12274 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 60400 No. of Facilities: 4594 (estimated) No. of Industries: 57 No. of Occupations: 47 No. of Employees: 64238 (estimated) No. of Female Employees: 23645 (estimated)

毒理学数据：

1.急性毒性^[18] LD50：5mg/kg（大鼠经口）

2.刺激性 暂无资料

3.致突变性^[19] DNA抑制：小鼠淋巴细胞1mmol/L。细胞遗传学分析：人淋巴细胞70mg/L（24h）。DNA损伤：大鼠肝300μmol/L。

生态数据：

1.生态毒性 暂无资料

2.生物降解性 暂无资料

3.非生物降解性 暂无资料

4.其他有害作用^[20] 该物质对环境有危害，应特别注意对水体的污染。

MSDS

Name:	Potassium Cyanide, Reagent ACS (Crystals), 96+% (Titr.) Material Safety Data Sheet
Synonym:	Cyanide of Potassium; Potassium Salt of Hydrocyanic Acid.
CAS:	151-50-8

Section 1 - Chemical ProductMSDS Name: Potassium Cyanide, Reagent ACS (Crystals), 96+% (Titr.) Material Safety Data Sheet
Synonym: Cyanide of Potassium; Potassium Salt of Hydrocyanic Acid. SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
151-50-8	POTASSIUM CYANIDE	96%	205-792-3

Hazard Symbols: T+
Risk Phrases: 26/27/28 32 SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Very toxic by inhalation, in contact with skin and if swallowed. Contact with acids liberates very toxic gas. Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye burns.
Skin:
May be absorbed through the skin in harmful amounts. Contact with skin causes irritation and possible burns, especially if the skin is wet or moist. If absorbed, causes symptoms similar to those of ingestion. Skin absorption may cause unconsciousness. Absorption into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Ingestion:
May be fatal if swallowed. Causes gastrointestinal tract burns. May cause tissue anoxia, characterized by weakness, headache, dizziness, confusion, cyanosis (bluish skin due to deficient oxygenation of the blood), weak and irregular heart beat, collapse, unconsciousness, convulsions, coma and death. Contains cyanide. Human fatalities have been reported from acute poisoning. Large doses of cyanide may result in suddden loss of consciousness and prompt death; small doses will prolong the above symptoms 1 to 2 hours.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Contains cyanide. Inhalation may result in symptoms similar to cyanide poisoning which include tachypnea, hyperpnea (abnormally rapid or deep breathing), and dyspnea (labored breathing) followed rapidly by respiratory depression. Pulmonary edema may occur.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated contact may cause skin necrosis and/or ulceration of the skin. Chronic exposure to cyanide solutions may lead to the development of a "cyanide" rash, characterized by itching, and by macular, papular, and vesicular eruptions, and may be accompanied by secondary infections. SECTION 4 - FIRST AID MEASURES
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Treat patient as for inhalation.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL! Treat patient as for inhalation.
Ingestion:
Get medical aid immediately. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE. Do not give anything by mouth. Treat patient as for inhalation.
Inhalation:
Remove from exposure to fresh air immediately. Do NOT use mouth-to-mouth resuscitation. Keep warm and at rest. Administer oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician:
Prompt action is essential in all cases of contact.
Antidote:
Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use. SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Do NOT use carbon dioxide. SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Decontaminate trace cyanide in the spill area with a strong sodium or calcium hypochlorite solution and flush waste to a holding area for potassium removal. SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from acids. SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Appearance: white
Odor: almond-like
pH: 11 (0.1N)
Vapor Pressure: 0 mm Hg
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 1173 deg F
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble in water
Specific Gravity/Density: 1.52
Molecular Formula: KCN
Molecular Weight: 65.105 SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials, moisture, acids, excess heat.
Incompatibilities with Other Materials:
Violent reactions can occur with oxidizing agents such as nitric acid, nitrates, and peroxides. Contact with acids liberates extremely toxic and flammable hydrogen cyanide gas. Hydrogen cyanide may form by a reaction with carbon dioxide and moisture when this material is in prolonged contact with air in a closed system.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides.
Hazardous Polymerization: Has not been reported. SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 151-50-8: TS8750000
LD50/LC50:
CAS# 151-50-8: Oral, mouse: LD50 = 8500 ug/kg; Oral, rabbit: LD50 = 5 mg/kg; Oral, rat: LD50 = 5 mg/kg.
Carcinogenicity:
POTASSIUM CYANIDE - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information. SECTION 12 - ECOLOGICAL INFORMATION Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA." SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. SECTION 14 - TRANSPORT INFORMATION IATA
Shipping Name: POTASSIUM CYANIDE
Hazard Class: 6.1
UN Number: 1680
Packing Group: I IMO
Shipping Name: POTASSIUM CYANIDE, SOLID
Hazard Class: 6.1
UN Number: 1680
Packing Group: I RID/ADR
Shipping Name: POTASSIUM CYANIDE
Dangerous Goods Code: 6.1(41A)
UN Number: 1680 SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with skin and if swallowed. R 32 Contact with acids liberates very toxic gas.
Safety Phrases:
S 1/2 Keep locked up and out of reach of children. S 7 Keep container tightly closed. S 24/25 Avoid contact with skin and eyes. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 28B After contact with skin, wash immediately with plenty of water and soap. S 29 Do not empty into drains. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 151-50-8: 3 United Kingdom Occupational Exposure Limits CAS# 151-50-8: OES-United Kingdom, TWA (listed as undefined ): as CN: 5 mg/m3 TWA; (does not include hydrogen cyanide, cyanogen or cyanogen chl Canada CAS# 151-50-8 is listed on Canada's DSL List. CAS# 151-50-8 is not listed on Canada's Ingredient Disclosure List. Exposure Limits CAS# 151-50-8: OEL-AUSTRALIA:TWA 5 mg/m3;Skin OEL-DENMARK:TWA 5 mg/m3;Skin OEL-SWITZERLAND:TWA 5 mg/m3;STEL 10 mg/m3;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV US FEDERAL TSCA CAS# 151-50-8 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 9/02/1997 Revision #3 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.
SECTION 16 - ADDITIONAL INFORMATION
N/A

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：无可用的

2、摩尔体积（cm³/mol）：无可用的

3、等张比容（90.2K）：无可用的

4、表面张力（dyne/cm）：无可用的

5、介电常数：无可用的

6、极化率（10^-24cm³）：无可用的

7、单一同位素质量：64.966781 Da

8、标称质量：65 Da

9、平均质量：65.1157 Da

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积23.8

7.重原子数量:3

8.表面电荷:0

9.复杂度:12.8

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:2