10H-Phenothiazine,2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-
- 中文别名：乙巯拉嗪
- 中文释义：乙巯匹拉嗪;吐来抗
- 英文别名：thiethylperazine;
Ethylthioperazine.;
Torecane;
Tietylperazine;
thietylperazine
- CAS No.：1420-55-9
- 分子式：
C22H29N3S2
- 分子量：399.61576
- 精确分子量：399.18000
- PSA：60.32000
- InChI：The Key: XCTYLCDETUVOIP-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.24g/cm3
- 沸点：
- 559.8ºC at 760mmHg
- 闪点：
- 292.4ºC
安全信息
- 密度：
- 1.24g/cm3
- 沸点：
- 559.8ºC at 760mmHg
- 闪点：
- 292.4ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SP0280000
- CHEMICAL NAME :
- Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-
- CAS REGISTRY NUMBER :
- 1420-55-9
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C22-H29-N3-S2
- MOLECULAR WEIGHT :
- 399.66
- WISWESSER LINE NOTATION :
- T C666 BN ISJ ES2 B3- AT6N DNTJ D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Rectal
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 857 ug/kg/2D-I
- TOXIC EFFECTS :
- Behavioral - ataxia
- REFERENCE :
- DICPBB Drug Intelligence and Clinical Pharmacy. (POB 42435, Cincinnati, OH 45242) V.3- 1969- Volume(issue)/page/year: 19,550,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 680 mg/kg
- TOXIC EFFECTS :
- Behavioral - antipsychotic
- REFERENCE :
- DNEUD5 Developments in Neuroscience (Amsterdam). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1977- Volume(issue)/page/year: 7,45,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 71600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,411,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4792 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1333 (estimated) No. of Female Employees: 656 (estimated)
