2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-
- 中文别名：替扎尼定
- 中文释义：替扎尼定;5-氯-4-(4,5-二氢-1H-咪唑-2-基)-2,1,3-苯并噻二唑-4-胺
- 英文别名：tizanidine;
Tizanidinum [INN-Latin];
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine;
Ternelin;
Tizanidina [INN-Spanish];
Sirdalud;
5-chloro-N-(imidazolidin-2-ylidene)-2,1,3-benzothiadiazol-4-amine;
UNII-6AI06C00GW;
Zanaflex(R);
Tizanidina;
[14C]-Tizanidine;
Zanaflex;
5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole;
Tizanidinum
- CAS No.：51322-75-9
- 分子式：
C9H8ClN5S
- 分子量：253.71
- 精确分子量：253.01900
- PSA：90.44000
- InChI：The Key: XFYDIVBRZNQMJC-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 外观与性状：
- 白色固体
- 密度：
- 1.82 g/cm3
- 熔点：
- 221 - 223ºC
- 沸点：
- 391.2ºC at 760 mmHg
- 闪点：
- 190.4ºC
安全信息
- 外观与性状：
- 白色固体
- 密度：
- 1.82 g/cm3
- 熔点：
- 221 - 223ºC
- 沸点：
- 391.2ºC at 760 mmHg
- 闪点：
- 190.4ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DL0080000
- CHEMICAL NAME :
- 2,1,3-Benzothiadiazole, 5-chloro-4-(2-imidazolin-2-ylamino)-
- CAS REGISTRY NUMBER :
- 51322-75-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H8-Cl-N5-S
- MOLECULAR WEIGHT :
- 253.73
- WISWESSER LINE NOTATION :
- T56 BNSNJ FM- BT5M CN BUTJ& GG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Skin and Appendages - hair
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,793,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 235 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Skin and Appendages - hair
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,793,1980
海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
