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5H-Dibenzo[b,e][1,4]diazepine,2-chloro-11-(4-methyl-1-piperazinyl)-

5H-Dibenzo[b,e][1,4]diazepine,2-chloro-11-(4-methyl-1-piperazinyl)-


  • 中文别名:2-氯-11-(4-甲基-1-哌嗪基)-5H-二苯并(b,e)(1,4)二氮杂卓
  • 中文释义:2-氯-11-(4-甲基-1-哌嗪基)-5H-二苯并(b,e)(1,4)二氮杂卓
  • 英文别名:8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine;
    2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine;
    ISOCLOZAPINE;
    5H-DIBENZO(b,e)(1,4)DIAZEPINE,2-CHLORO-11-(4-METHYL-1-PIPERAZINYL);
    2-Chloro-11-(4-methyl-1-piperazinyl)-5H-benzo(b,e)(1,4)diazepine;
    8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine;
    2-chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 
  • CAS No.:1977-08-8
  • 分子式:C18H19ClN4
  • 分子量:0
  • 精确分子量:326.13000
  • PSA:30.87000
  • 分子结构式:

物化性质

蒸汽压:
1.62E-09mmHg at 25°C

安全信息

蒸汽压:
1.62E-09mmHg at 25°C

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP1700000
CHEMICAL NAME :
5H-Dibenzo(b,e)(1,4)diazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
CAS REGISTRY NUMBER :
1977-08-8
BEILSTEIN REFERENCE NO. :
0763655
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H19-Cl-N4
MOLECULAR WEIGHT :
326.86
WISWESSER LINE NOTATION :
T C676 BM INJ MG J- AT6N DNTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,841,1965

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