3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-
- 中文别名：格帕沙星
- 中文释义：格帕沙星;1-环丙基-6-氟-7-(3-甲基-1-哌嗪基)-5-甲基-1,4-二氢-4-氧代喹啉-3-羧酸;格里沙星
- 英文别名：Grepafloxacin;
1-Cyclopropyl-6-fluoro-7-(3-methyl-1-piperazinyl)-5-methyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid;
1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;
1-cyclopropyl-5-methyl-6-fluoro-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
- CAS No.：119914-60-2
- 分子式：C19H22FN3O3
- 分子量：359.39
- 精确分子量：359.16500
- PSA：74.57000
- InChI：The Key: AIJTTZAVMXIJGM-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.366
- 熔点：
- 189-192ºC
- 沸点：
- 610ºC at 760mmHg
- 闪点：
- 322.7ºC
安全信息
- 密度：
- 1.366
- 熔点：
- 189-192ºC
- 沸点：
- 610ºC at 760mmHg
- 闪点：
- 322.7ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB1993785
- CHEMICAL NAME :
- 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-5-methyl-7-(3-meth yl- 1-piperazinyl)-4-oxo-
- CAS REGISTRY NUMBER :
- 119914-60-2
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H22-F-N3-O3
- MOLECULAR WEIGHT :
- 359.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 78 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 22,4531,1994
