b-D-Fructopyranose
- 中文别名：果糖
- 中文释义：果糖;左旋糖
- 英文别名：β-D-fructopyranose;
fructosteril;
laevosan;
beta-D-fructopyranose;
Frutabs;
(2R,3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol;
beta-D-Fructopyranose;
laevoral;
levugen;
(D)-fructose
- CAS No.：7660-25-5
- 分子式：C6H12O6
- 分子量：180.16
- 精确分子量：180.06300
- PSA：110.38000
- InChI：The Key: LKDRXBCSQODPBY-YMFWUOAHSA-N
- 分子结构式：
物化性质
- 外观与性状：
- 白色结晶粉末
- 密度：
- 1.758 g/cm3
- 熔点：
- 100 - 110ºC
- 沸点：
- 401.1ºC at 760 mmHg
- 闪点：
- 196.4ºC
- 折射率：
- 1.5101 (108ºC)
安全信息
- 外观与性状：
- 白色结晶粉末
- 密度：
- 1.758 g/cm3
- 熔点：
- 100 - 110ºC
- 沸点：
- 401.1ºC at 760 mmHg
- 闪点：
- 196.4ºC
- 折射率：
- 1.5101 (108ºC)
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LS7000000
- CHEMICAL NAME :
- Fructopyranose, beta-D-
- CAS REGISTRY NUMBER :
- 7660-25-5
- BEILSTEIN REFERENCE NO. :
- 1423189
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H12-O6
- MOLECULAR WEIGHT :
- 180.18
- WISWESSER LINE NOTATION :
- T6OTJ BQ B1Q CQ DQ EQ FRUCTO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,254,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,254,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,254,1990
- TYPE OF TEST :
- LD30 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 16,580,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,72,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 13350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,254,1990 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5000 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 46,371,1955
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