5,6-Dithia-2,9,11-triazatridecanamide,13-chloro-N-(2-chloroethyl)-N,11-dinitroso-10-oxo-
- 中文别名：1-(2-氯乙基)-3-[2-[2-[(2-氯乙基-亚硝基-氨基甲酰)氨基]乙基二巯基]乙基]-1-亚硝基-脲
- 英文别名：1-(2-chloroethyl)-3-[2-[2-[[2-chloroethyl(nitroso)carbamoyl]amino]ethyldisulfanyl]ethyl]-1-nitrosourea;
Ditiomustine;
CNCC;
I.C.I.G. 1325
- CAS No.：77469-44-4
- 分子式：C10H18Cl2N6O4S2
- 分子量：421.36
- 精确分子量：420.02100
- PSA：201.14000
- InChI：The Key: XWPCYYOZOJKYKQ-UHFFFAOYSA-N
- 分子结构式：
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT2150000
- CHEMICAL NAME :
- Urea, 1,1'-dithiodiethylenebis(3-(2-chloroethyl)-3-nitroso-
- CAS REGISTRY NUMBER :
- 77469-44-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H18-Cl2-N6-O4-S2
- MOLECULAR WEIGHT :
- 421.36
- WISWESSER LINE NOTATION :
- ONNG2&VM2SS2MVNNO&2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 20 mg/L
- REFERENCE :
- INSSDM INSERM Symposium. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) No.1- 1975- Volume(issue)/page/year: 19,229,1981
