1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-
- 中文别名：三氟噻吨; 4-(3-(2-(三氟甲基)-9H-噻吨-9-亚基)丙基)-1-哌嗪乙醇
- 中文释义：三氟噻吨;4-(3-(2-(三氟甲基)-9H-噻吨-9-亚基)丙基)-1-哌嗪乙醇
- 英文别名：flupenthixol;
n7009;
[3H]-(Z)-Flupentixol;
siplaril;
fluanxol;
Flupentiol;
fluxanxol;
emergil;
siplarol;
lc44;
flupentixol
- CAS No.：2709-56-0
- 分子式：
C23H25F3N2OS
- 分子量：434.52
- 精确分子量：434.16400
- PSA：52.01000
- InChI：The Key: NJMYODHXAKYRHW-DVZOWYKESA-N
- 分子结构式：
物化性质
- 外观与性状：
- 白色或灰白色固体
- 密度：
- 1.306g/cm3
- 沸点：
- 554.7ºC at 760mmHg
- 闪点：
- 289.3ºC
- 折射率：
- 1.607
安全信息
- 外观与性状：
- 白色或灰白色固体
- 密度：
- 1.306g/cm3
- 沸点：
- 554.7ºC at 760mmHg
- 闪点：
- 289.3ºC
- 折射率：
- 1.607
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL9900000
- CHEMICAL NAME :
- 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl )-
- CAS REGISTRY NUMBER :
- 2709-56-0
- LAST UPDATED :
- 199507
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H25-F3-N2-O-S
- MOLECULAR WEIGHT :
- 434.56
- WISWESSER LINE NOTATION :
- T C666 BS IYJ IU3- AT6N DNTJ D2Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 900 ug/kg
- TOXIC EFFECTS :
- Behavioral - sleep Behavioral - changes in motor activity (specific assay) Behavioral - coma
- REFERENCE :
- DICPBB Drug Intelligence and Clinical Pharmacy. (POB 42435, Cincinnati, OH 45242) V.3- 1969- Volume(issue)/page/year: 15,388,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 367 ug/kg/12D-I
- TOXIC EFFECTS :
- Behavioral - wakefulness Behavioral - muscle weakness Behavioral - headache
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,93,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,2121,1977
