5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]-,(5Z)-
- 中文别名：依替前列通; (5Z)-7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E)-2-[2-(苯氧基甲基)-1,3-二氧环戊-2-基]乙烯基]环戊基]-5-庚烯酸
- 中文释义：依替前列通;(5Z)-7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E)-2-[2-(苯氧基甲基)-1,3-二氧环戊-2-基]乙烯基]环戊基]-5-庚烯酸;依替前列酮
- 英文别名：(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-2-[2-(phenoxymethyl)-1,3-dioxolan-2-yl]ethenyl]cyclopentyl]hept-5-enoic acid;
(5Z,13E)-(8R,9S,11R,12R)-9,11-dihydroxy-15,15-ethylenedioxy-16-phenoxy-17,18,19,20-tetranor-prostadienoic acid;
Etiprostone;
Etiprostone [INN-French];
Etiproston;
Etiproston (INN);
Etiprostonum [INN-Latin];
Etiprostonum
- CAS No.：59619-81-7
- 分子式：C24H32O7
- 分子量：432.51
- 精确分子量：432.21500
- PSA：105.45000
- InChI：The Key: BPALXSWPHQNCAA-RLJNYRALSA-N
- 分子结构式：
物化性质
- 密度：
- 1.297g/cm3
- 沸点：
- 598.1ºC at 760 mmHg
- 折射率：
- 1.633
安全信息
- 密度：
- 1.297g/cm3
- 沸点：
- 598.1ºC at 760 mmHg
- 折射率：
- 1.633
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9671000
- CHEMICAL NAME :
- 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(2-(2-(phenoxymethyl)-1,3-dioxolan -2-yl)ethenyl) cyclopentyl)-, (1R-(1-alpha(Z),2-beta(E),3-alpha,5-alpha))-
- CAS REGISTRY NUMBER :
- 59619-81-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H32-O7
- MOLECULAR WEIGHT :
- 432.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 600 ug/kg
- SEX/DURATION :
- female 4-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,443,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 25 ug/kg
- SEX/DURATION :
- female 29 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - physical
- REFERENCE :
- ANIPA8 Animal Production. (Scotish Academic Press Ltd., 33 Montgomery Street, Edinburgh EH7 5JX, UK) V.1- 1959- Volume(issue)/page/year: 49,129,1989
