sodium,[4-[(5-methoxypyrimidin-2-yl)sulfamoyl]phenyl]azanide
- 中文别名：磺胺对甲氧嘧啶钠
- 中文释义：磺胺对甲氧嘧啶钠;2-Hydroxy-4-iodobenzoic Acid Methyl Ester;4-Iodosalicylic Acid Methyl Ester;methyl 2-hydroxy-4-iodobenzoate;METHYL 4-IODOSALICYLATE;(1S,5S)-6,6-dimethyl-2-methylidenebicyclo[3.1.1]heptane;(1S)-(1)-Beta-Pinene;(1S)-(-)-Beta-Pinene;gamma-chlor
- 英文别名：sodium,[4-[(5-methoxypyrimidin-2-yl)sulfamoyl]phenyl]azanide;
Sulfametorine sodium;
5-Methoxysulfadiazine sodium;
Sulfameter sodium;
N(sup 1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide,sodium salt;
Sulfamethoxydiazine sodium;
Methoxypyrimal sodium;
Sulfa-5-methoxypyrimidine sodium salt;
2-Sulfanilamido-5-methoxypyrimidine sodium salt;
2-(p-Aminobenzenesulfonamido)-5-methoxypyrimidine sodium salt;
4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide sodium salt
- CAS No.：18179-67-4
- 分子式：
C11H11N4NaO3S
- 分子量：302.28500
- 精确分子量：302.04500
- PSA：103.55000
- InChI：InChI=1/C11H11N4O3S.Na/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10;/h2-7,12H,1H3,(H,13,14,15);/q-1;+1
- 分子结构式：
物化性质
- 沸点：
- 539.4ºC at 760mmHg
- 闪点：
- 280ºC
- 蒸汽压：
- 1.05E-11mmHg at 25°C
安全信息
- 沸点：
- 539.4ºC at 760mmHg
- 闪点：
- 280ºC
- 蒸汽压：
- 1.05E-11mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WP0600000
- CHEMICAL NAME :
- Sulfanilamide, N(sup 1)-(5-methoxy-2-pyrimidinyl)-, sodium salt
- CAS REGISTRY NUMBER :
- 18179-67-4
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C11-H11-N4-O3-S.Na
- MOLECULAR WEIGHT :
- 302.31
- WISWESSER LINE NOTATION :
- T6N CNJ BMSWR DZ& EO1 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,695,1961
