9H-Purin-2-amine,6-[(phenylmethyl)thio]-
- 中文别名：6-[(苯基甲基)硫代]-1H-嘌呤-2-胺
- 英文别名：6-benzylsulfanyl-7H-purin-2-amine;
2-Amino-6-benzylmercaptopurine;
SRI 702;
Benzylthioguanine;
6-Benzylthioguanine;
2-amino-6-[(phenylmethyl)thio]purine;
2-Amino-6-benzyl-MP;
6-benzylsulfanyl-7(9)H-purin-2-ylamine;
Benzythioguanine;
Purine,2-amino-6-(benzylthio);
6-(benzylsulfanyl)-9H-purin-2-amine;
2-amino-6-(benzyl-thio)purine;
S6-benzyl-6-thioguanine;
6-[(phenylmethyl)thio]-1H-purin-2-amine
- CAS No.：1874-58-4
- 分子式：C12H11N5S
- 分子量：257.34
- 精确分子量：257.07400
- PSA：105.78000
- InChI：The Key: JQMGATKUPCKDEG-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.5g/cm3
- 沸点：
- 441.7ºC at 760 mmHg
- 闪点：
- 220.9ºC
- 折射率：
- 1.789
- 蒸汽压：
- 5.34E-08mmHg at 25°C
- 存储条件/存储方法：
- 低温通风干燥,与库房食品原料分开存放
安全信息
- 密度：
- 1.5g/cm3
- 沸点：
- 441.7ºC at 760 mmHg
- 闪点：
- 220.9ºC
- 折射率：
- 1.789
- 蒸汽压：
- 5.34E-08mmHg at 25°C
- 存储条件/存储方法：
- 低温通风干燥,与库房食品原料分开存放
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UO7501000
- CHEMICAL NAME :
- Purine, 2-amino-6-(benzylthio)-
- CAS REGISTRY NUMBER :
- 1874-58-4
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H11-N5-S
- MOLECULAR WEIGHT :
- 257.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 222 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 4,291,1962
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- female 7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 4,291,1962
