1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-
- 中文别名：环苯扎林; 5-(3-二甲氨基亚丙基)二苯并[a,d]环庚三烯
- 中文释义：环苯扎林;甲普罗替林;去氢替林;3-chloro-10,11-dihydro-N,N-dimethyl-5H-Dibenz(b,f)azepine-5-propanamine;3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine;3-Chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine;5-(g-Dimethylamin
- 英文别名：cyclobenzaprine;
Cyclobenz;
Yurelax;
Flexeril;
Proeptatriene;
Cyclobenzaprinum;
3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine;
Proheptatrien;
Proheptatriene;
Ciclobenzaprina;
Lisseril
- CAS No.：303-53-7
- 分子式：
C20H21N
- 分子量：275.39
- 精确分子量：275.16700
- PSA：3.24000
- InChI：InChI=1/C20H21N.ClH/c1-21(2)13-7-11-19-15-17-9-4-3-8-16(17)14-18-10-5-6-12-20(18)19;/h3-6,8-12,14-15H,7,13H2,1-2H3;1H/b19-11-;
- 分子结构式：
物化性质
- 外观与性状：
- 固体
- 密度：
- 1.096 g/cm3
- 沸点：
- 405.9ºC at 760 mmHg
- 闪点：
- 177.8ºC
安全信息
- 外观与性状：
- 固体
- 密度：
- 1.096 g/cm3
- 沸点：
- 405.9ºC at 760 mmHg
- 闪点：
- 177.8ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HP0550000
- CHEMICAL NAME :
- 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 303-53-7
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H21-N
- MOLECULAR WEIGHT :
- 275.42
- WISWESSER LINE NOTATION :
- L C676 BY&T&J BU3N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,338,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 36 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970
海关数据
中国海关编码：2921499090
- 概述：
- 2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
