2-Propen-1-one,1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-
- 中文别名：桂哌齐特; 1-(吡咯烷-1-基甲酰甲基)-4-(3,4,5-三甲氧基肉桂酰基)哌嗪
- 中文释义：桂哌齐特;桂哌各特;1-(吡咯烷-1-基甲酰甲基)-4-(3,4,5-三甲氧基肉桂酰基)哌嗪
- 英文别名：1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one;
Piperazine,1-((1-pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl);
Cinepazide;
EINECS 245-928-9;
Piperazine,1-(2-oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl);
1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-4-[3-(3,4,5-trimethoxy-phenyl)-acryloyl]-piperazine;
1-(PYRROLIDIN-1-YLCARBONYLMETHYL)-4-(3,4,5-TRIMETHOXYCINNAMOYL)PIPERAZINE;
1-((1-Pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine;
Cinepazidum [INN-Latin];
Cinepazida [INN-Spanish]
- CAS No.：23887-46-9
- 分子式：C22H31N3O5
- 分子量：417.50
- 精确分子量：417.22600
- PSA：71.55000
- InChI：InChI=1/C22H31N3O5/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24/h6-7,14-15H,4-5,8-13,16H2,1-3H3/b7-6+
- 分子结构式：
物化性质
- 外观与性状：
- 白色粉末
- 密度：
- 1.2 g/cm3
- 熔点：
- 170 - 175ºC
- 沸点：
- 637.8ºC at 760 mmHg
- 闪点：
- 339.5ºC
- 折射率：
- 1.574
- 蒸汽压：
- 3.65E-16mmHg at 25°C
安全信息
- 外观与性状：
- 白色粉末
- 密度：
- 1.2 g/cm3
- 熔点：
- 170 - 175ºC
- 沸点：
- 637.8ºC at 760 mmHg
- 闪点：
- 339.5ºC
- 折射率：
- 1.574
- 蒸汽压：
- 3.65E-16mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM2486800
- CHEMICAL NAME :
- Piperazine, 1-(2-oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-t rimethoxyphenyl)-2-pr openyl)-
- CAS REGISTRY NUMBER :
- 23887-46-9
- BEILSTEIN REFERENCE NO. :
- 0903854
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H31-N3-O5
- MOLECULAR WEIGHT :
- 417.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 44640 mg/kg/31D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - proteinuria Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,375,1979
