1-Propanone,1-[4-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy]phenyl]-
- 中文别名：Centpropazine; 1-{4-[2-羟基-3-(4-苯基-1-哌嗪基)丙氧基]苯基}-1-丙酮
- 中文释义：3Β-羟基-孕甾-16-烯-20-酮-3-醋酸酯;1-{4-[2-羟基-3-(4-苯基-1-哌嗪基)丙氧基]苯基}-1-丙酮
- 英文别名：1-[4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]phenyl]propan-1-one;
Centpropazine;
Centropazine
- CAS No.：34675-77-9
- 分子式：
C22H28N2O3
- 分子量：368.47
- 精确分子量：368.21000
- PSA：53.01000
- InChI：The Key: ZQPXSRTZFYHSFB-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.147g/cm3
- 沸点：
- 560.7ºC at 760mmHg
- 闪点：
- 292.9ºC
- 折射率：
- 1.576
安全信息
- 密度：
- 1.147g/cm3
- 沸点：
- 560.7ºC at 760mmHg
- 闪点：
- 292.9ºC
- 折射率：
- 1.576
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC2984000
- CHEMICAL NAME :
- 1-Propanone, 1-(4-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phe nyl)-
- CAS REGISTRY NUMBER :
- 34675-77-9
- BEILSTEIN REFERENCE NO. :
- 0578135
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H28-N2-O3
- MOLECULAR WEIGHT :
- 368.52
- WISWESSER LINE NOTATION :
- T6N DNTJ A1YQ1OR DV2& DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1710 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,338,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 270 mg/kg
- TOXIC EFFECTS :
- Behavioral - wakefulness
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,286,1972
海关数据
中国海关编码：2933599090
- 概述：
- 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
