1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,1,2,3,4,5,6-hexahydro-3-methyl-, monohydriodide, (1R)- (9CI)
- 中文别名：N-甲基金雀花碱氢碘酸盐
- 中文释义：N-甲基金雀花碱氢碘酸盐;CAULOPHYLLINE HYDRIODIDE;N-METHYLCYTISINE HYDRIODIDE
- 英文别名：Caulophylline hydriodide;
(1R)-3-Methyl-1,2,3,4,5,6-hexahydro-1r,5c-methano-pyrido[1,2-a][1,5]diazocin-8-on,Hydroiodid;
Caulophylline,monohydriodide;
(1R)-3-methyl-1,2,3,4,5,6-hexahydro-1r,5c-methano-pyrido[1,2-a][1,5]diazocin-8-one,hydriodide;
N-Methylcytisine hydriodide;
CYTISINE,12-METHYL-,HYDROGEN IODIDE;
N-methylcytisine,monohydroiodide,(1R-cis)-isomer;
C12H17N2O.I;
(-)-7R:9S-Caulophylline hydrogen iodide;
Caulophyllinehydriodide;
Caulophylline,monohydriodide (8CI)
- CAS No.：20013-22-3
- 分子式：
C12H16N2O.HI
- 分子量：331.17
- 精确分子量：332.03900
- PSA：34.03000
- InChI：The Key: OVECGORDPUPRLI-BAUSSPIASA-N
- 分子结构式：
物化性质
- 沸点：
- 408.9ºC at 760 mmHg
- 闪点：
- 201.1ºC
- 蒸汽压：
- 6.75E-07mmHg at 25°C
安全信息
- 沸点：
- 408.9ºC at 760 mmHg
- 闪点：
- 201.1ºC
- 蒸汽压：
- 6.75E-07mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA4550000
- CHEMICAL NAME :
- Cytisine, 12-methyl-, hydrogen iodide
- CAS REGISTRY NUMBER :
- 20013-22-3
- LAST UPDATED :
- 199207
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H16-N2-O.H-I
- MOLECULAR WEIGHT :
- 332.21
- WISWESSER LINE NOTATION :
- T C666 A GVN LM&TTJ &IH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >830 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 51 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- REFERENCE :
- BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- REFERENCE :
- BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969
