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2(1H)-Quinolinone,5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-

2(1H)-Quinolinone,5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-


  • 中文别名:卡替洛尔; 5-[3-(叔丁基氨基)-2-羟基丙氧基]-3,4-二氢-1H-喹啉-2-酮
  • 中文释义:卡替洛尔;喹诺酮心安
  • 英文别名:carteolol;
    Carteololum;
    Carteolol [INN:BAN];
    Carteololum [INN-Latin];
    5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one;
    CARTEOLOL;
    Ocupress;
    Carteolol HCl;
    Carteolol Monohydrochloride;
    Carteolol (INN);
    5-(3-tert-butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one;
    5-[3-(1,1-dimethylethyl)amino-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone 
  • CAS No.:51781-06-7
  • 分子式:C16H24N2O3
  • 分子量:292.37
  • 精确分子量:292.17900
  • PSA:70.59000
  • InChI:The Key: LWAFSWPYPHEXKX-UHFFFAOYSA-N
  • 分子结构式:

物化性质

密度:
1.13 g/cm3
沸点:
518.6ºC at 760 mmHg
闪点:
267.4ºC
存储条件/存储方法:
库房低温通风干燥

安全信息

密度:
1.13 g/cm3
沸点:
518.6ºC at 760 mmHg
闪点:
267.4ºC
存储条件/存储方法:
库房低温通风干燥

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC8281000
CHEMICAL NAME :
2(1H)-Quinolinone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4 -dihydro-
CAS REGISTRY NUMBER :
51781-06-7
LAST UPDATED :
199112
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C16-H24-N2-O3
MOLECULAR WEIGHT :
292.42
WISWESSER LINE NOTATION :
T66 BMVT&J GO1YQ1MX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJTOEX Japanese Journal of Toxicology. (Yakugyo Jihosha, Hokushin Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo, 101, Japan) V.1- 1988- Volume(issue)/page/year: 4,121,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
830 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
740 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
112 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

海关数据

中国海关编码:2933790090

概述:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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