1H-Benz[de]isoquinoline-1,3(2H)-dione,5-amino-2-[2-(dimethylamino)ethyl]-
- 中文别名：氨萘非特; 5-氨基-2-[2-(二甲基氨基)乙基]-1H-苯并[de]异喹啉-1,3(2H)-二酮
- 中文释义：氨萘非特;5-氨基-2-[2-(二甲基氨基)乙基]-1H-苯并[DE]异喹啉-1,3(2H)-二酮
- 英文别名：5-amino-2-[2-(dimethylamino)ethyl]benzo[de]isoquinoline-1,3-dione;
Amonafidum [Latin];
Amonifide;
Xanafide;
Amonafide;
Nafidimide;
5-amino-2-[(dimethylamine)ethyl]-1H-benz[de-]isoquinoline-1,3-(2H)-dione;
Benzisoquinolinedione;
2-(2-dimethylaminoethyl)-5-aminobenzo[de]isoquinoline-1,3-dione;
Quinamed;
5-Aminomitonafide;
5-amino-2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
- CAS No.：69408-81-7
- 分子式：
C16H17N3O2
- 分子量：283.32
- 精确分子量：283.13200
- PSA：68.33000
- InChI：The Key: UPALIKSFLSVKIS-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.306g/cm3
- 熔点：
- 162-164ºC
- 沸点：
- 500.2ºC at 760 mmHg
- 闪点：
- 256.3ºC
- 折射率：
- 1.681
安全信息
- 密度：
- 1.306g/cm3
- 熔点：
- 162-164ºC
- 沸点：
- 500.2ºC at 760 mmHg
- 闪点：
- 256.3ºC
- 折射率：
- 1.681
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QK5610000
- CHEMICAL NAME :
- Naphthalimide, 3-amino-N-(2-(dimethylamino)ethyl)-
- CAS REGISTRY NUMBER :
- 69408-81-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C16-H17-N3-O2
- MOLECULAR WEIGHT :
- 283.36
- WISWESSER LINE NOTATION :
- T666 1A M CVNVT&&J D2N1&1 HZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 67 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >18400 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3845,1985
