1-Octadecanamine,N,N-dimethyl-

物化性质

外观与性状：

透明液体

密度：

0.8

熔点：

23 °C

沸点：

347 °C

闪点：

155 °C

水溶解性：

Slightly soluble

折射率：

1.45

蒸汽压：

5.03E-05mmHg at 25°C

存储条件/存储方法：

塑料桶装，每桶50kg。贮存于阴凉、通风处。远离火种和热源。

塑料桶装，每桶50kg。长途运输时外用木条箱，桶底衬稻草。

稳定性相关：

1.基本性质：可与环氧乙烷、硫酸二甲酯、硫酸二乙酯、氯甲烷、氯苄等反应，生成不同的季铵盐阳离子。

2.本品低毒。
　

其它信息：

1、性状：浅棕色粘稠液体，20℃时为浅草黄软质固体

2、熔点（℃）：22.5

3、沸点（℃）：202

4、相对密度：0.84

5、溶解性：易溶于醇类溶剂，不溶于水

6、凝固点（℃）：22.89

安全信息

外观与性状：

透明液体

密度：

0.8

熔点：

23 °C

沸点：

347 °C

闪点：

155 °C

水溶解性：

Slightly soluble

折射率：

1.45

蒸汽压：

5.03E-05mmHg at 25°C

存储条件/存储方法：

塑料桶装，每桶50kg。贮存于阴凉、通风处。远离火种和热源。

塑料桶装，每桶50kg。长途运输时外用木条箱，桶底衬稻草。

稳定性相关：

1.基本性质：可与环氧乙烷、硫酸二甲酯、硫酸二乙酯、氯甲烷、氯苄等反应，生成不同的季铵盐阳离子。

2.本品低毒。
　

其它信息：

1、性状：浅棕色粘稠液体，20℃时为浅草黄软质固体

2、熔点（℃）：22.5

3、沸点（℃）：202

4、相对密度：0.84

5、溶解性：易溶于醇类溶剂，不溶于水

6、凝固点（℃）：22.89

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

RG4200000

CHEMICAL NAME :

Octadecylamine, N,N-dimethyl

CAS REGISTRY NUMBER :

124-28-7

BEILSTEIN REFERENCE NO. :

1763346

LAST UPDATED :

199710

DATA ITEMS CITED :

7

MOLECULAR FORMULA :

C20-H43-N

MOLECULAR WEIGHT :

297.64

WISWESSER LINE NOTATION :

18N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,440,1986

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,440,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,11,1953

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

315 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 26,517,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4163 No. of Facilities: 64 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 1624 (estimated) No. of Female Employees: 90 (estimated)

毒理学数据：

皮肤/眼睛刺激性：标准德来塞实验

兔子皮肤接触，20mg/24HREACTION SEVERITY，中等反应；

兔子眼睛接触，20mg/24HREACTION SEVERITY，强烈反应；

急性毒性数据：大鼠腹腔LDLo：100mg/kg；小鼠腹腔LD50：315mg/kg

MSDS

Name:	N N-Dimethyloctadecylamine (Techn) 89% (GC) Material Safety Data Sheet
Synonym:	Dimethylstearamine; Dymanthine
CAS:	124-28-7

Section 1 - Chemical Product   MSDS Name:N N-Dimethyloctadecylamine (Techn) 89% (GC) Material Safety Data Sheet
Synonym:Dimethylstearamine; Dymanthine
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
124-28-7	N,N-Dimethyloctadecylamine	89	204-694-8

Hazard Symbols: C
Risk Phrases: 10 34
Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Flammable. Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin burns. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Ingestion of large amounts may cause CNS depression. May cause systemic effects.
Inhalation:
Causes chemical burns to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. May cause burning sensation in the chest.
Chronic:
Effects may be delayed.
Section 4 - FIRST AID MEASURES
  Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
  Handling:
Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame.
Avoid ingestion and inhalation. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 124-28-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: colorless
Odor: amine-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 23 deg C
Autoignition Temperature: Not available.
Flash Point: 44 deg C ( 111.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: .8000g/cm3
Molecular Formula: C20H43N
Molecular Weight: 297.57
Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 124-28-7: RG4200000 LD50/LC50:
CAS# 124-28-7: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate.
Carcinogenicity:
N,N-Dimethyloctadecylamine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
 
Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: Amines, liquid, corrosive, n.o.s.*
Hazard Class: 8 (3)
UN Number: 2735
Packing Group: III
IMO
Shipping Name: Amines, liquid, corrosive, n.o.s.
Hazard Class: 8 (3)
UN Number: 2735
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.
Hazard Class: 8
UN Number: 2920
Packing group: II
Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 10 Flammable.
R 34 Causes burns.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 25 Avoid contact with eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 124-28-7: 2
Canada
CAS# 124-28-7 is listed on Canada's DSL List.
CAS# 124-28-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 124-28-7 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

海关数据

中国海关编码：2921199090

概述：

2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途

摘要/Summary：

2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

分子结构与计算化学数据

分子结构数据

1、 摩尔折射率：98.42

2、 摩尔体积（cm³/mol）：365.9

3、 等张比容（90.2K）：853.5

4、 表面张力（dyne/cm）：29.6

5、 极化率（10-24cm3）：39.01

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:1

4.可旋转化学键数量:17

5.互变异构体数量:无

6.拓扑分子极性表面积3.2

7.重原子数量:21

8.表面电荷:0

9.复杂度:177

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1