8H-13,3,6a-Ethanylylidene-7,10-methanooxepino[3,4-i]-1-benzazocin-8-one,1-ethyltetradecahydro-12a,14-dihydroxy-6-methoxy-3-methyl-,(3R,6S,6aS,7R,7aS,10S,12aS,13R,13aR,14S,15R)-
- 中文别名：(3R,6S,6aS,7R,7aS,10S,12aS,13R,13aR,14S,15R)-1-乙基十四氢-12a,14-二羟基-6-甲氧基-3-甲基-8H-13,3,6a-亚乙基-7,10-甲桥氧杂卓并[3,4-i]-1-苯并氮杂环辛四烯-8-酮
- 中文释义：HETERATISINE
- 英文别名：HETERATISINE;
7-Ethyl-10-methoxy-20-deoxyaminocamptothecin;
20-deoxyamino-7-ethyl-10-methoxycamptothecin
- CAS No.：3328-84-5
- 分子式：C22H33NO5
- 分子量：391.56
- 精确分子量：391.23600
- PSA：79.23000
- InChI：The Key: YPSAOPXJHSESSR-AGBQGJAZSA-N
- 分子结构式：
物化性质
- 密度：
- 1.33g/cm3
- 沸点：
- 583.2ºC at 760mmHg
- 闪点：
- 306.5ºC
- 折射率：
- 1.612
安全信息
- 密度：
- 1.33g/cm3
- 沸点：
- 583.2ºC at 760mmHg
- 闪点：
- 306.5ºC
- 折射率：
- 1.612
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MK6800000
- CHEMICAL NAME :
- Heteratisan-14-one, 6,8-dihydroxy-20-ethyl-1-methoxy-4-methyl-, (1-alpha,6-beta)-
- CAS REGISTRY NUMBER :
- 3328-84-5
- BEILSTEIN REFERENCE NO. :
- 0052343
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H33-N-O5
- MOLECULAR WEIGHT :
- 391.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 254 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 15,180,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 15,180,1984
