5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-a-lyxo-hexopyranosyl]oxy]-,hydrochloride, (8S,10S)- (9CI)
- 中文别名:3-羟基乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基2,3,6-三脱氧-3-(4-吗啉基)吡喃己糖苷
- 英文别名:5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(4-morpholinyl)-.α.-L-lyxo-hexopyranosyl]oxy]-, hydrochloride, (8S-cis)-;
Morpholinoadriamycin;
(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[(2S,4S,5S,6S)-5-hydroxy-6-methyl-4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride
- CAS No.:89196-04-3
- 分子式:C31H35NO12.ClH
- 分子量:0
- 精确分子量:649.19300
- PSA:192.52000
- InChI:The Key: INAUWOVKEZHHDM-PEDBPRJASA-N
- 分子结构式:
物化性质
- 沸点:
- 842.4ºC at 760 mmHg
- 闪点:
- 463.2ºC
安全信息
- 沸点:
- 842.4ºC at 760 mmHg
- 闪点:
- 463.2ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9426040
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(hydroxyacetyl)-1-methoxy-10-(( 2,3,6-trideoxy- 3-(4-morpholinyl)-alpha-lyxo-hexopyranosyl)oxy)-6,8,1 1-trihydroxy-, hydrochloride, (8S-cis)-
- CAS REGISTRY NUMBER :
- 89196-04-3
- LAST UPDATED :
- 199303
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C31-H35-N-O12.Cl-H
- MOLECULAR WEIGHT :
- 650.13
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Musculoskeletal - other changes Nutritional and Gross Metabolic - dehydration
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211144
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 90 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Blood - changes in bone marrow (not otherwise specified) Musculoskeletal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211144