2H-Pyran-2-one,4-methoxy-6-[(1E)-2-phenylethenyl]-
- 中文别名：去甲氧基醉椒素
- 中文释义：去甲氧基醉椒素;(E)-4-甲氧基-6-苯乙烯基-2H-吡喃-2-酮;卡文内酯
- 英文别名：Desmethoxy Yangonin;
Desmethoxyyangonin;
DIHYDROKAVAIN;
(E)-4-Methoxy-6-(2-phenylethenyl)-2H-pyran-2-one,5,6-Dehydrokavain,Demethoxyyangonin
- CAS No.：15345-89-8
- 分子式：C14H12O3
- 分子量：228.24300
- 精确分子量：228.07900
- PSA：39.44000
- InChI：InChI=1/C14H12O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-10H,1H3/b8-7+
- 分子结构式：
物化性质
- 外观与性状：
- 白色至淡的黄色粉末
- 密度：
- 1.18 g/cm3
- 熔点：
- 138-140ºC
- 沸点：
- 440ºC at 760 mmHg
- 闪点：
- 188ºC
- 折射率：
- 1.588
- 蒸汽压：
- 6.09E-08mmHg at 25°C
安全信息
- 外观与性状：
- 白色至淡的黄色粉末
- 密度：
- 1.18 g/cm3
- 熔点：
- 138-140ºC
- 沸点：
- 440ºC at 760 mmHg
- 闪点：
- 188ºC
- 折射率：
- 1.588
- 蒸汽压：
- 6.09E-08mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ1240000
- CHEMICAL NAME :
- 2H-Pyran-2-one, 4-methoxy-6-styryl-, (E)-
- CAS REGISTRY NUMBER :
- 15345-89-8
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H12-O3
- MOLECULAR WEIGHT :
- 228.26
- WISWESSER LINE NOTATION :
- T6OVJ DO1 F1U1R DO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
