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azane; 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetracarboxylate; platinum(+2) cation

azane; 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetracarboxylate; platinum(+2) cation


  • 中文别名:(1aR,1bS,4R,4aS,7aS,7bS,8R,9R,9aS)-9a-(乙酰氧基)-4,4a,7b-三羟基-1,1,3,6,8-五甲基-5-羰基-1a,1b,4,4a,5,7a,7b,8,9,9a-十氢-1H-环丙烯并[3,4]苯并[1,2-e]薁-9-基 2-{[2-(甲基氨基)苯甲酰]氨基}苯酸酯
  • 中文释义:(1aR,1bS,4R,4aS,7aS,7bS,8R,9R,9aS)-9a-(乙酰氧基)-4,4a,7b-三羟基-1,1,3,6,8-五甲基-5-羰基-1a,1b,4,4a,5,7a,7b,8,9,9a-十氢-1H-环丙烯并[3,4]苯并[1,2-e]薁-9-基 2-{[2-(甲基氨基)苯甲酰]氨基}苯酸酯;Platinum(2+) 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetr acarboxylate ammoniate (2:1:4
  • 英文别名:Platinum(2+) 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetr acarboxylate ammoniate (2:1:4) 
  • CAS No.:128163-25-7
  • 分子式:C16H32N4O14Pt2
  • 分子量:894.6117
  • 精确分子量:894.12100
  • PSA:228.86000
  • 分子结构式:

物化性质

沸点:
798.9ºC at 760 mmHg
闪点:
283.7ºC
蒸汽压:
5.06E-28mmHg at 25°C

安全信息

沸点:
798.9ºC at 760 mmHg
闪点:
283.7ºC
蒸汽压:
5.06E-28mmHg at 25°C

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2507100
CHEMICAL NAME :
Platinum, tetraamine(mu-(1,4,7,10,13,16-hexaoxacyclooctadecane- 2,3,11,12-tetracarbox ylato(4-)-O(sup 2),O(sup 3),O(sup 11),O(sup 12))di-
CAS REGISTRY NUMBER :
128163-25-7
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H32-N4-O14-Pt2
MOLECULAR WEIGHT :
894.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - rat Ovary
DOSE/DURATION :
20 umol/L
REFERENCE :
EJCAEL European Journal of Cancer. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.26-28(2/3), 1990-92. For publisher information, see EJCTEA Volume(issue)/page/year: 27,62,1991

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