azane; 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetracarboxylate; platinum(+2) cation
- 中文别名:(1aR,1bS,4R,4aS,7aS,7bS,8R,9R,9aS)-9a-(乙酰氧基)-4,4a,7b-三羟基-1,1,3,6,8-五甲基-5-羰基-1a,1b,4,4a,5,7a,7b,8,9,9a-十氢-1H-环丙烯并[3,4]苯并[1,2-e]薁-9-基 2-{[2-(甲基氨基)苯甲酰]氨基}苯酸酯
- 中文释义:(1aR,1bS,4R,4aS,7aS,7bS,8R,9R,9aS)-9a-(乙酰氧基)-4,4a,7b-三羟基-1,1,3,6,8-五甲基-5-羰基-1a,1b,4,4a,5,7a,7b,8,9,9a-十氢-1H-环丙烯并[3,4]苯并[1,2-e]薁-9-基 2-{[2-(甲基氨基)苯甲酰]氨基}苯酸酯;Platinum(2+) 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetr acarboxylate ammoniate (2:1:4
- 英文别名:Platinum(2+) 1,4,7,10,13,16-hexaoxacyclooctadecane-2,3,11,12-tetr acarboxylate ammoniate (2:1:4)
- CAS No.:128163-25-7
- 分子式:C16H32N4O14Pt2
- 分子量:894.6117
- 精确分子量:894.12100
- PSA:228.86000
- 分子结构式:
物化性质
- 沸点:
- 798.9ºC at 760 mmHg
- 闪点:
- 283.7ºC
- 蒸汽压:
- 5.06E-28mmHg at 25°C
安全信息
- 沸点:
- 798.9ºC at 760 mmHg
- 闪点:
- 283.7ºC
- 蒸汽压:
- 5.06E-28mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2507100
- CHEMICAL NAME :
- Platinum, tetraamine(mu-(1,4,7,10,13,16-hexaoxacyclooctadecane- 2,3,11,12-tetracarbox ylato(4-)-O(sup 2),O(sup 3),O(sup 11),O(sup 12))di-
- CAS REGISTRY NUMBER :
- 128163-25-7
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H32-N4-O14-Pt2
- MOLECULAR WEIGHT :
- 894.70
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - rat Ovary
- DOSE/DURATION :
- 20 umol/L
- REFERENCE :
- EJCAEL European Journal of Cancer. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.26-28(2/3), 1990-92. For publisher information, see EJCTEA Volume(issue)/page/year: 27,62,1991