2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide
- 中文别名：乙噻嗪
- 中文释义：乙噻嗪;乙氢氯噻嗪
- 英文别名：6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;
Neo-diuresal;
Ethiazidum [INN-Latin];
Etiazide [DCIT];
Aethiazidum;
ETHIAZIDE;
6-Chlor-7-sulfamoyl-3-aethyl-1,1-dioxy-3,4-dihydro-2H-1,2,4-benzothiadiazin;
6-Chlor-3-aethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxid;
Etiazida [INN-Spanish];
6-Chlor-3-aethyl-1,1-dioxy-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazin;
Salta;
Eclotizidum;
6-Chlor-7-sulfamoyl-3-aethyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxid;
3-Ethylhydrochlorothiazide;
Ethiazide [INN:BAN:JAN]
- CAS No.：1824-58-4
- 分子式：
C9H12ClN3O4S2
- 分子量：325.81
- 精确分子量：324.99600
- PSA：135.12000
- InChI：The Key: VXLCNTLWWUDBSO-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.526g/cm3
- 沸点：
- 563.5ºC at 760mmHg
- 闪点：
- 294.6ºC
- 折射率：
- 1.589
- 蒸汽压：
- 1.01E-12mmHg at 25°C
安全信息
- 密度：
- 1.526g/cm3
- 沸点：
- 563.5ºC at 760mmHg
- 闪点：
- 294.6ºC
- 折射率：
- 1.589
- 蒸汽压：
- 1.01E-12mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DK9460000
- CHEMICAL NAME :
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide
- CAS REGISTRY NUMBER :
- 1824-58-4
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C9-H12-Cl-N3-O4-S2
- MOLECULAR WEIGHT :
- 325.81
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,110,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,110,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
海关数据
中国海关编码：2935009090
- 概述：
- 2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
