9H-Pyrido[2,3-b]indol-2-amine,3-methyl-
- 中文别名:2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚
- 中文释义:2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚;2-氨基-3-甲基-9H-吡啶并[2,3-b]吲哚
- 英文别名:3-methyl-9H-pyrido[2,3-b]indol-2-amine;
Glob-P-1
- CAS No.:68006-83-7
- 分子式:C12H11N3
- 分子量:197.2
- 精确分子量:197.09500
- PSA:54.70000
- InChI:The Key: IVLCGFRPPGNALI-UHFFFAOYSA-N
- 分子结构式:
物化性质
- 密度:
- 1.334g/cm3
- 熔点:
- 215-218ºC
- 沸点:
- 443.2ºC at 760mmHg
- 闪点:
- 252.1ºC
- 折射率:
- 1.806
安全信息
- 密度:
- 1.334g/cm3
- 熔点:
- 215-218ºC
- 沸点:
- 443.2ºC at 760mmHg
- 闪点:
- 252.1ºC
- 折射率:
- 1.806
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU9354380
- CHEMICAL NAME :
- 9H-Pyrido(2,3-b)indole, 2-amino-3-methyl-
- CAS REGISTRY NUMBER :
- 68006-83-7
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C12-H11-N3
- MOLECULAR WEIGHT :
- 197.26
- WISWESSER LINE NOTATION :
- T B656 FN HMJ D1 EZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32800 mg/kg/85W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37380 mg/kg/64W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35424 mg/kg/70W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- DNA adduct
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 125 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 269,79,1992 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
海关数据
中国海关编码:2933990090
- 概述:
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素:
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
- 摘要/Summary:
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%