cephaeline hydrochloride
- 中文别名：盐酸吐根酚碱
- 中文释义：吐根酚碱氯化氢;(-)-CEPHAELINE, DIHYDROCHLORIDE
- 英文别名：(-)-CEPHAELINE, DIHYDROCHLORIDE;
10,11,7'-Trimethoxy-emetan-6'-ol,Hydrochlorid;
cephaeline dihydrochloride;
10,11,7'-trimethoxy-emet-1'-ene-9,6'-diol;
Alangicine;
10,11,7'-trimethoxy-emetan-6'-ol,dihydrochloride;
10,11,7'-Trimethoxy-emetan-6'-ol,Dihydrochlorid
- CAS No.：5853-29-2
- 分子式：C28H38N2O4?2ClH
- 分子量：539.60
- 精确分子量：502.26000
- PSA：63.19000
- InChI：The Key: NWYUGUJIBCMDEB-QJAXAJGISA-N
- 分子结构式：
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FJ9450000
- CHEMICAL NAME :
- Cephaeline hydrochloride
- CAS REGISTRY NUMBER :
- 5853-29-2
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C28-H38-N2-O4.2Cl-H
- MOLECULAR WEIGHT :
- 539.60
- WISWESSER LINE NOTATION :
- T B666 GNTT&J E2 LO1 MO1 D1- BT66 CMT&J HQ IO1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,421,1952
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 10,73,1917/1918
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 74970 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20530 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 10,73,1917/1918
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