9,10-Ethanoanthracene-9(10H)-methanamine,N-methyl-, hydrochloride (1:1)
- 中文别名：盐酸苯佐卡因
- 中文释义：盐酸苯佐卡因
- 英文别名：Benzoctamine hydrochloride;
Benzoctamine HCl;
Tacitin;
Tacitine;
EINECS 233-216-0;
BA 30,803
- CAS No.：10085-81-1
- 分子式：C18H19N.ClH
- 分子量：285.84
- 精确分子量：285.12800
- PSA：12.03000
- 分子结构式：
物化性质
- 沸点：
- 372ºC at 760mmHg
- 闪点：
- 181.1ºC
- 蒸汽压：
- 9.91E-06mmHg at 25°C
- 存储条件/存储方法：
- 通风低温干燥
安全信息
- 沸点：
- 372ºC at 760mmHg
- 闪点：
- 181.1ºC
- 蒸汽压：
- 9.91E-06mmHg at 25°C
- 存储条件/存储方法：
- 通风低温干燥
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KJ4550000
- CHEMICAL NAME :
- 9,10-Ethanoanthracene-9-(10H)-methylamine, N-methyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 10085-81-1
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C18-H19-N.Cl-H
- MOLECULAR WEIGHT :
- 285.84
- WISWESSER LINE NOTATION :
- L6 H666/GP 2AF P&&TTJ G1M1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,336,1972 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 51 mg/kg
- SEX/DURATION :
- female 2-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 1927- Volume(issue)/page/year: 49,1309,1973
